AI Article Synopsis

  • The posterior fossa syndrome (PFS) can occur after surgery in the posterior fossa, leading to symptoms like temporary mutism and personality changes, although cases with a non-tumoral cause are rare.
  • A 12-year-old girl experienced PFS symptoms after a stroke caused by a ruptured arteriovenous malformation (AVM), first becoming mute and exhibiting severe anxiety and irritability.
  • After a few days, her mutism improved following surgery to remove the AVM, making this the first documented case of PFS arising from non-surgical cerebellar damage.

Article Abstract

The posterior fossa syndrome (PFS) is a well-known clinical consequence of posterior fossa surgery that has only been reported in a limited number of cases with a nontumoral etiology. It consists of transient cerebellar mutism, behavioral abnormalities and personality changes. We describe a 12-year-old child who developed transient cerebellar mutism associated with behavioral and emotional symptoms following rupture of a vermis arteriovenous malformation (AVM). Following the stroke, the girl experienced a 24-hour symptom-free interval. After that, she became mute and her emotional state was characterized by severe anxiety, irritability and withdrawal. After 3 days, mutism resolved and dysarthria became apparent. Two weeks after stroke, the AVM was surgically removed and the postoperative course was uneventful. This case is the first reported in which the PFS occurred after focal nonsurgically induced cerebellar damage.

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Source
http://dx.doi.org/10.1159/000106388DOI Listing

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