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How do women with Rokitansky syndrome and healthcare professionals reflect on the provision of uterine transplantation? Insights from an interview study in France, Norway, and Sweden.
Acta Obstet Gynecol Scand
January 2025
Centre for Medical Ethics, University of Oslo, Oslo, Norway.
Introduction: Uterine transplantation is currently intended for women with absolute uterine infertility. Since proof of the concept in 2014, many countries have started research programs and clinical activities. However, access to uterine transplantation remains limited given that only a few hundred transplants have been described worldwide compared with the 1.
View Article and Find Full Text PDFPregnancy challenges and outcomes among female physicians.
Discoveries (Craiova)
September 2024
Pennsylvania State University, Penn State College of Medicine, Hershey, PA.
Article Synopsis
- Female physicians are becoming a larger part of the workforce but face significant challenges with family planning due to demanding work hours, limited parental leave, and potential stigma.
- The study aimed to identify factors affecting fertility and pregnancy complications among U.S. female physicians, such as age, stress, and working conditions, noting that those in surgical fields experience higher rates of infertility and complications.
- Despite their increasing numbers, female physicians still struggle with balancing personal and professional lives, highlighting the need for more research and better policies to support their reproductive health and family planning.
Circular RNAs as a novel class of potential therapeutic and diagnostic biomarkers in reproductive biology/diseases.
Eur J Med Res
December 2024
School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Infertility is a prevalent problem among 10% of people within their reproductive years. Sometimes, even advanced treatment options like assisted reproduction technology have the potential to result in failed implantation. Because of the expected changes in gene expression during both in vitro and in vivo fertilization processes, these methods of assisting fertility have also been associated with undesirable pregnancy outcomes related to infertility.
View Article and Find Full Text PDFA case of assisted reproductive technology-induced maternal alloimmunization: an emerging sensitizing factor to consider?
Immunohematology
December 2024
Transfusion Medicine, Dr. Rela Institute & Medical Centre, Bharath Institute of Higher Education and Research, Chennai, Tamilnadu, India.
Red blood cell (RBC) alloimmunization can occur because of exposure to various sensitizing factors and poses a constant threat in transfusion. Assisted reproductive technology (ART) involves manipulation of sperm, ova, or embryos with the goal of producing a pregnancy. We present an interesting case of ART-induced maternal alloimmunization (AIMA) due to anti-c in a woman carrying a twin pregnancy.
View Article and Find Full Text PDFEpigenetics of oogenesis.
Arch Gynecol Obstet
December 2024
Faculty of Medicine, Department of Medical Biology and Genetics, University of Rijeka, Braće Branchetta 20, 51000, Rijeka, Croatia.
Epigenetic changes include all modifications affecting the expression of genes without changing the nucleotide sequence of the genome. Most studied epigenetic changes include DNA methylation, histone alterations and non-coding RNAs. DNA methylation is an important epigenetic mark, protecting the genome during gametogenesis and early embryo development.
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