Leiomyomatosis peritonealis disseminata is an uncommon condition characterized by subperitoneal proliferation of benign nodules mainly composed of benign smooth muscle cells. This entity generally appears in premenopausal women and hormonal influences may play a role in its pathogenesis. The macroscopic appearance mimics peritoneal carcinomatosis. The characteristic clinical course is asymptomatic and diagnosis is only feasible after microscopic examination. To date, less than 100 cases have been reported in the literature. We report the case of a 40-year-old woman who underwent surgery in our department.
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http://dx.doi.org/10.1016/s0009-739x(07)71680-9 | DOI Listing |
J Obstet Gynaecol Res
January 2025
Department of Obstetrics and Gynecology, Fujita Health University, Bantane Hospital, Nagoya, Japan.
Parasitic myoma is a relatively rare disease in which one or more leiomyomas form outside the uterus; however, the detailed causes are unknown. Few sporadic reports are available, and per our research, the maximum number of parasitic myomas reported to date was 26, and almost all cases were treated by surgical resection. We report a rare case of numerous parasitic myomas in the abdominal cavity, possibly including an intrathoracic lesion, which could not be resected completely.
View Article and Find Full Text PDFBMJ Case Rep
June 2024
Obstetrics and Gynecology, All India Institute of Medical Sciences Jodhpur, Jodhpur, Rajasthan, India.
Disseminated peritoneal leiomyomatosis (DPL) is a rare and benign clinical entity. It is also known as leiomyomatosis peritonealis disseminata (LPD). Here, we report and discuss a case of a primiparous woman in her early 40s who presented with heavy, prolonged, painful menses and heaviness in her lower abdomen.
View Article and Find Full Text PDFBMC Med
March 2024
Department of Obstetrics and Gynecology, National Clinical Research Center for Obstetric & Gynecologic Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Fengzhi Feng, No. 1, Shuaifuyuan, Beijing, 100730, Wangfujing, China.
Background: Intravenous leiomyomatosis (IVL), pulmonary benign metastatic leiomyomatosis (PBML), and leiomyomatosis peritonealis disseminata (LPD) are leiomyomas with special growth patterns and high postoperative recurrence rates. We report the safety and efficacy of a pilot study of sirolimus in the treatment of recurrent IVL, PBML, and recurrent LPD.
Methods: This was a pilot study to evaluate the safety and efficacy of sirolimus in the treatment of leiomyomatosis (ClinicalTrials.
Clin Nucl Med
February 2024
Department of Obstetrics and Gynecology, Qingpu Branch, Zhongshan Hospital Affiliated to Fudan University, Shanghai, China.
A 35-year-old woman with a history of laparoscopic myomectomy presented with repeated abdominal pain. Contrast-enhanced abdominal and pelvic CT showed multiple enhancing solid or mixed cystic and solid peritoneal masses, and an enhancing uterine mass. All these masses showed intense FDG uptake on FDG PET/CT.
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