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Intramolecular distance-regulated G4 DNA enzymatic activity-based chromophotometric system for visual monitoring of diquat.
Anal Chim Acta
January 2025
Key Laboratory of Luminescence Analysis and Molecular Sensing (Southwest University), Ministry of Education, College of Chemistry and Chemical Engineering, Southwest University, Chongqing, 400715, PR China. Electronic address:
Background: As global food production continues to surge, the widespread use of herbicides has also increased concurrently, posing challenges like health risks and environmental pollution. Traditional detection methods for pesticide residues, such as diquat (DQ), were hampered by limitations like high expenses, lengthy detection times and complex operations, restricting their practical application in rapid clinical diagnosis.
Results: In light of the pressing necessity for the identification of minute pesticide residues and the intrinsic constraints of small molecule analysis, a novel chromophotometric biosensor targeting small molecules was developed based on bi-epitopes on single antibody to immobilize two DQ-PAL, inhibiting the hybridization of DQ-PAL.
Effectiveness of shared decision making strategies for stroke prevention among patients with atrial fibrillation: cluster randomized controlled trial.
BMJ
January 2025
Department of Population Health Sciences, University of Utah, Salt Lake City VA Informatics, Decision-Enhancement and Analytic Sciences, Salt Lake City, UT, USA.
Objective: To evaluate the effectiveness of multiple decision aid strategies in promoting high quality shared decision making for prevention of stroke in patients with non-valvular atrial fibrillation.
Design: Cluster randomized controlled trial.
Setting: Six academic medical centers in the United States.
Can microplastic pollution be affected by beach nourishment? Assessment in intertidal sediment and bivalves.
Sci Total Environ
January 2025
Laboratory of Coastal Biology and Microplastic Analysis, Department of Chemistry, Federal University of Espírito Santo, Brazil.
Several methods can be used to mitigate coastal erosion, and one of the leading solutions is known as beach nourishment (BN), which involves using dredged material for nourishment, adding sand to extend an eroding beach. Although it has many advantages, the environmental impacts of BN remain poorly understood, especially on plastic pollution, which had not been investigated until this study. We aimed to compare the abundance and distribution of microplastics (MPs) found in intertidal sediments and specimens of the bivalve mollusks Crassostrea brasiliana, Mytella strigata, Perna perna, and Tivela mactroides, collected in two beaches of Vitoria, Southeast of Brazil (da Costa et al.
View Article and Find Full Text PDFSacral Neuromodulation Reprogramming Rates: Understanding Office-Based Requirement.
Urogynecology (Phila)
December 2024
Importance: Sacral neuromodulation (SNM) is a procedure with the advantage of reprogramming for discomfort or inadequate symptom control.
Objectives: The aims of this study were to investigate the rates of office-based SNM programming in a large multisite cohort and to examine differences based on implantation indication.
Study Design: The TriNetX database was utilized for retrospective cohort comparison using International Classification of Diseases, Tenth Revision, and Current Procedural Terminology (CPT) codes.
Dexamethasone Intravitreal Injection in Diabetic Patients Undergoing Cataract Surgery: an updated literature review.
Retina
January 2025
Ophthalmology Clinic, Department of Biomedical Sciences, University of Messina, Italy.
Purpose: This literature review synthetizes current evidence on the timing and efficacy of dexamethasone intravitreal injections for diabetic macular edema (DME) in patients undergoing cataract surgery, particularly phacoemulsification, to determine the optimal timing for improved outcome.
Methods: A systematic review of the literature was conducted across key databases to identify peer-reviewed studies, clinical trials, and meta-analyses addressing dexamethasone injections administered pre-, intra-, and post-operatively for DME in the context of cataract surgery. Studies were selected based on relevance to timing, visual outcomes, and inflammation control, with a focus on comparative efficacy.
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