AI Article Synopsis
- The study aimed to assess the prevalence of pneumococcal bacteria in the noses of young children in London daycare centers and to examine their antibiotic resistance and serotype distribution.
- During the survey from March to November 2003, swabs were taken from 234 children, revealing that over half carried pneumococci but showed low resistance to penicillin.
- The findings highlighted a high rate of pneumococcal carriage, with notable differences related to ethnicity and a need for ongoing monitoring of vaccine-related serotypes.
Article Abstract
Objective: To estimate the prevalence of nasopharyngeal (NP) carriage of pneumococcus (Streptococcus pneumoniae) and describe the antibiotic resistance patterns and serotypes in young children attending group day care in London.
Design And Subjects: Cross-sectional survey of attendees at a sample of registered child day care centres (CDCCs) in a London borough.
Setting: Urban setting with a socially and culturally diverse population.
Methods And Outcomes: 19 CDCCs (13% of total) participated between March and November 2003. A single NP swab was required from each child, and parents completed a questionnaire about their child's health and attendance at day care. WHO methodology for pneumococcal carriage studies was followed.
Results: 30% of parents consented. 234 swabs were collected from children aged 6 months to 5 years. 53% were boys and 81% were white. 120 children (51%, 95% CI 45% to 58%) carried pneumococci in their nasopharynx. None of the isolates were resistant to penicillin (upper CL 3%). 21 isolates were resistant to erythromycin (17.5%, 95% CI 11% to 25.5%). 68 isolates (57%) were serotypes included in the 7-valent conjugate vaccine. Non-white children had a lower prevalence of carriage (27% vs 58%).
Conclusion: The prevalence of pneumococcal NP carriage was high. The penicillin resistance rate is lower than in many other countries and may reflect a decrease in community antibiotic prescribing in the UK. Monitoring circulating serotypes is important in the context of recent changes to the vaccination policy. Further study is required to explore the association with ethnicity and risk factors for antibiotic resistance.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2066083 | PMC |
| http://dx.doi.org/10.1136/adc.2007.126359 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Effectiveness of Synchronous Postdischarge Contacts on Health Care Use and Patient Satisfaction : A Systematic Review and Meta-analysis.
Ann Intern Med
January 2025
Center of Innovation to Accelerate Discovery and Practice Transformation, Durham Veterans Affairs Health Care System; Department of Population Health Sciences, Duke University School of Medicine; and Durham Evidence Synthesis Program, Durham Veterans Affairs Health Care System, Durham, North Carolina (J.M.G.).
Background: Postdischarge contacts (PDCs) after hospitalization are common practice, but their effectiveness in reducing use of acute care after discharge remains unclear.
Purpose: To assess the effects of PDC on 30-day emergency department (ED) visits, 30-day hospital readmissions, and patient satisfaction.
Data Sources: MEDLINE, Embase, and CINAHL searched from 2012 to 25 May 2023.
Jargon and Readability in Plain Language Summaries of Health Research: Cross-Sectional Observational Study.
J Med Internet Res
January 2025
Department of Health and Community Sciences, University of Exeter Medical School, University of Exeter, Exeter, United Kingdom.
Background: The idea of making science more accessible to nonscientists has prompted health researchers to involve patients and the public more actively in their research. This sometimes involves writing a plain language summary (PLS), a short summary intended to make research findings accessible to nonspecialists. However, whether PLSs satisfy the basic requirements of accessible language is unclear.
View Article and Find Full Text PDFDischarge Disposition after Total Hip Arthroplasty: A 10-Year Analysis of Trends and Predictors of Nonhome Discharge (2011-2021).
J Am Acad Orthop Surg
January 2025
From the Department of Orthopedic Surgery, Cleveland Clinic Foundation, Cleveland, OH (Pasqualini, Ibaseta, T Khan, and Piuzzi), the Case Western Reserve University School of Medicine, Cleveland, OH (Pan, Xu, and Austin), the Department of Orthopaedic Surgery, Larkin Community Hospital, South Miami, FL (Corces), and Levitetz Department of Orthopaedic Surgery, the Cleveland Clinic Florida, Weston, FL (Higuera).
Background: Total hip arthroplasty (THA) practices are evolving under the influence of the current value-based healthcare system and bundled payment models. This study aimed to (1) evaluate national trends in discharge disposition and postoperative outcomes after THA, (2) compare discharge cohorts on episode-of-care parameters, and (3) determine predictors of nonhome discharge from 2011 to 2021.
Methods: The National Surgical Quality Improvement Program database was queried for THA data from 2011 to 2021.
Improving Cognitive Empathy Through Traumatic Brain Injury Experiential Learning: A Novel Mixed Methods Approach for Speech-Language Pathology Graduate Education.
Am J Speech Lang Pathol
January 2025
Good Samaritan Medical Center Foundation, Lafayette, CO.
Purpose: The aim of this study was to gauge the impacts of cognitive empathy training experiential learning on traumatic brain injury (TBI) knowledge, awareness, confidence, and empathy in a pilot study of speech-language pathology graduate students.
Method: A descriptive quasi-experimental convergent parallel mixed methods design intervention pilot study (QUAL + QUANT) was conducted with a diverse convenience sample of 19 first- and second-year speech-language pathology graduate students who engaged in a half-day TBI point-of-view simulation. The simulation was co-constructed through a participatory design with those living with TBI based on Kolb's experiential learning model and followed the recommendations for point-of-view simulation ethics.
Intravaginal cooling provides symptom relief in women with vulvovaginal candidiasis and reduces immunopathology in an accompanying mouse model.
J Infect Dis
January 2025
Department of Oral and Craniofacial Biology, School of Dentistry, LSU Health New Orleans, USA.
Background: Vulvovaginal candidiasis (VVC), caused primarily by Candida albicans, is currently treated with either prescription or over-the-counter antifungal drugs, often with variable efficacy and relapses. New and improved therapeutic strategies, including drug-free treatment alternatives, are needed. Upon overgrowth or environmental triggers, C.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!