Self-reported use of gamma-hydroxybutyrate (GHB) among clubbers has increased over the last decade, and is often reported in the scientific literature in association with negative events such as amnesia, overdose, and use in drug facilitated sexual assault. However, there has been relatively little work investigating the phenomenology of GHB intoxication, and the reasons underlying use. In this study, 189 individuals reporting at least one lifetime use of GHB completed an online questionnaire recording GHB use behaviours, GHB use function, and subjective GHB effects. The most frequently reported primary GHB use functions were for recreation (but not in nightclubs) (18.3%); to enhance sex (18.3%); to be sociable (13.1%); and to explore altered states of consciousness (13.1%). GHB was more commonly used within the home (67%) compared to nightlife environments (26.1%) such as clubs, although this differed on the basis of respondent's sexuality. Principle components analysis of GHB user responses to the subjective questionnaire revealed six components: general intoxication effects, positive intoxication effects, negative intoxication effects, negative physiological effects, positive sexual effects and negative sexual effects. Component scores predicted function of use.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1016/j.drugalcdep.2007.07.009 | DOI Listing |
CNS Drugs
January 2025
Cognitive and Clinical Neuroimaging Core, McLean Hospital, McLean Imaging Center, Belmont, MA, USA.
The relationship between cannabis use and mental health is complex, as studies often report seemingly contradictory findings regarding whether cannabis use results in more positive or negative treatment outcomes. With an increasing number of individuals using cannabis for both recreational (i.e.
View Article and Find Full Text PDFJMIR AI
January 2025
Human-Computer Interaction and Human-Centered AI Systems Lab, AI for Healthcare Lab, Charles V. Schaefer, Jr. School of Engineering and Science, Stevens Institute of Technology, Hoboken, NJ, United States.
Background: Acute marijuana intoxication can impair motor skills and cognitive functions such as attention and information processing. However, traditional tests, like blood, urine, and saliva, fail to accurately detect acute marijuana intoxication in real time.
Objective: This study aims to explore whether integrating smartphone-based sensors with readily accessible wearable activity trackers, like Fitbit, can enhance the detection of acute marijuana intoxication in naturalistic settings.
Food Chem Toxicol
December 2024
Clinical Biochemistry and Mechanistic Toxicology Research Cluster, Department of Biochemistry, Federal University of Agriculture, Abeokuta, Ogun State, Nigeria.
Dichlorvos (DDVP) is an organophosphate insecticide that enhances food production and repels disease vectors. However, it provokes cytotoxicity. 2S-hesperidin (2S-HES) is a potent antioxidant, anti-inflammatory, and anti-lipidemic flavanone.
View Article and Find Full Text PDFJ Hazard Mater
December 2024
School of Public Health, Guangzhou Medical University, Guangzhou 511436, China. Electronic address:
The burden of N-(1,3-dimethylbutyl)-N'-phenyl-p-phenylenediamine (6PPD) and its oxidized products on human health can no longer be ignored due to the detection types and concentrations in the environment continue to increase. Environmental ozone (O) and ultraviolet A (UVA) may induce ozonation and photoaging of 6PPD to produce toxic products. However, the impact of specific environmental conditions on the aging and toxic effects of 6PPD is unclear.
View Article and Find Full Text PDFArch Sex Behav
December 2024
Department of Psychology, Carleton University, 1125 Colonel By Drive, Ottawa, ON, K1S 5B6, Canada.
Among young adults, engaging in sexting (i.e., sharing sexually explicit materials of oneself with others) can be a healthy and normative sexual experience.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!