The emission concentrations of carbonyl compounds in air were quantified from a total of 195 man-made source units within 77 individual companies at a large industrial complex in Korea. The measurement data were evaluated both by absolute magnitude of concentration and by their relative contribution to malodor formation such as malodor degree (MD) derived from empirical formula. It was found that formaldehyde exhibited the highest mean concentration of 323ppb with a median value of 28.2ppb, while butyraldehyde recorded the highest contribution to odor formation with an MD value of 3.5 (186 (mean) and 9.8ppb (median)). The relative intensity of carbonyl emission, when compared by the sum of MD, showed the highest source strength from the food and beverage (industry sector) and scrubber (source unit). A comprehensive evaluation of the carbonyl data from diverse industrial facilities thus allowed us to describe the fundamental patterns of their emission.
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http://dx.doi.org/10.1016/j.chemosphere.2007.07.025 | DOI Listing |
Org Lett
January 2025
State Key Laboratory of Applied Organic Chemistry & College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou, Gansu 730000, P. R. China.
Herein, we present a visible-light-induced protocol for the synthesis of highly functionalized oxo-bridged oxocine skeletons. This method generates carbenes via visible-light-induced ortho-acyl diazo compounds, which are rapidly intercepted by the oxygen atom of an intermolecular acyl group to form a cyclic 1,3-dipole. The in situ generated highly reactive 1,3-dipole undergoes a facile formal [4 + 3] cycloaddition with alkenyl pyrazolinone, yielding [4.
View Article and Find Full Text PDFAngew Chem Int Ed Engl
January 2025
The Scripps Research Institute, Department of Chemistry, 10550 North Torrey pines Road, BCC-169, 92037, La Jolla, UNITED STATES OF AMERICA.
Electrochemical, fully stereoselective P(V)-radical hydrophosphorylation of olefins and carbonyl compounds using a P(V) reagent is disclosed. By strategically selecting the anode material, radical reactivity is accessible for alkene hydrophosphorylation whereas a polar pathway operates for ketone hydrophosphorylation. The mechanistic intricacies of these chemoselective transformations were explored in-depth.
View Article and Find Full Text PDFTurk J Biol
October 2024
Department of Biology, Faculty of Science, Gazi University, Ankara, Turkiye.
Background/aim: The hyperglycemic environment in diabetes disrupts normal wound-healing processes, leading to chronic wounds. This study investigated whether the combination of the phenolic compounds ellagic acid and carnosic acid shows synergistic effects on diabetic wound healing and oxidative parameters in diabetic rats.
Materials And Methods: Diabetic rats were divided into control, untreated, Carbopol 974P treated, topical treatment, and oral gavage treatment groups.
J Med Chem
January 2025
Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Viale F. Stagno D'Alcontres, 31-98166 Messina, Italy.
Aldo-keto reductase 1B10 (AKR1B10) is a human enzyme that catalyzes the NADPH-dependent reduction of several different carbonyl compounds to the corresponding alcohols. Under physiological conditions, AKR1B10 is expressed mainly in the gastrointestinal tract, where it can detoxify reactive carbonyl compounds derived from dietary sources and xenobiotics. AKR1B10 is highly expressed in several cancers and precancerous conditions, proving to be crucially implicated in carcinogenesis and to function as a prognostic indicator of tumor development.
View Article and Find Full Text PDFChemistryOpen
January 2025
Universidad de Buenos Aires, Facultad de Farmacia y Bioquímica, Department of Chemistry, Ciudad Autónoma de Buenos Aires, 1113, Argentina.
Gem-diols are defined as organic molecules carrying two hydroxyl groups at the same carbon atom, which is the result of the nucleophilic addition of water to a carbonyl group. In this work, the generation of the hydrated or hemiacetal forms using pyridine- and imidazole-carboxaldehyde isomers in different chemical environments was studied by Nuclear Magnetic Resonance (NMR) recorded in different media and combined with theoretical calculations. The change in the position of aldehyde group in either the pyridine or the imidazole ring had a clear effect in the course of the hydration/hemiacetal generation reaction, which was favored in protic solvents mainly in the presence of methanol.
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