Object: Conduct disorder (CD) and attention deficit hyperactivity disorder (ADHD) may be more prevalent in relatives of alcoholics and may predict alcohol and drug problems, but not all studies agree. This paper evaluates these questions in well-educated families of alcoholics and controls.
Methods: Data from 165, 14-25-year-old offspring in the San Diego Prospective Study were used to create Group 1 (n=17) with CD or ADHD and Group 2 (n=148) with no such diagnoses. Correlations and hierarchical logistic regressions evaluated characteristics associated with these disorders, comparing the impact of CD and ADHD.
Results: The rates of CD (6.1%) and of ADHD (4.8%) were not strikingly elevated, and did not relate to the family history of alcohol or drug use disorders. Group 1 offspring were more likely to have divorced parents, a relative with bipolar disorder, a higher intake of alcohol and illicit substances, and associated problems.
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http://dx.doi.org/10.1016/j.jpsychires.2007.07.013 | DOI Listing |
BMC Pediatr
January 2025
Nutrition & Health Innovation Research Institute, Edith Cowan University, Perth, WA, Australia.
Background: Growing evidence shows that dysregulated metabolic intrauterine environments can affect offspring's neurodevelopment and behaviour. However, the results of individual cohort studies have been inconsistent. We aimed to investigate the association between maternal diabetes before pregnancy and gestational diabetes mellitus (GDM) with neurodevelopmental, cognitive and behavioural outcomes in children.
View Article and Find Full Text PDFPhysiol Behav
January 2025
Departamento de Biología de la Reproducción. D.C.B.S, Universidad Autónoma Metropolitana-Iztapalapa, San Rafael Atlixco 186, Col. Vicentina, C.P, 09340, Ciudad de México, México. Electronic address:
Phytoestrogens are non-steroidal compounds that, can act as agonists and/or antagonists by binding to estrogen receptors; hence they can modify estrogen-dependent processes of neonatal sexual differentiation. Results of the analysis of the sexual behavior of experimental rats that received 6.8 mg of isoflavones/kg/day, showed significantly more mating activity, but fewer ejaculations (p<0.
View Article and Find Full Text PDFAlzheimers Dement
January 2025
Department of Epidemiology and Biostatistics, University of California, San Francisco, California, USA.
Introduction: The association between adult child educational attainment and older parent's cognitive health may vary across diverse contexts but cross-national comparisons have been limited by differences in outcome assessment, study design, and analytic choices.
Methods: We used harmonized data with comprehensive cognitive assessments from the United States (N = 3088), India (N = 3828), and Mexico (N = 1875) to estimate associations between adult child education and older adults' cognitive functioning using linear regression models adjusted for respondent and family-level socio-economic status (SES) in each study.
Results: Each additional year of offspring education was associated with 0.
Alzheimers Dement
January 2025
Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, California, USA.
Introduction: We compared the relationship between offspring education and cognitive health outcomes among Hispanic and White adults.
Methods: We used data from Hispanic and White (1998-2018) United States (US) Health and Retirement Study (HRS) participants (n = 17,484). We assessed cognitive function and decline using episodic memory scores in linear mixed models and incident cognitive impairment with no dementia (CIND) or probable dementia using the Langa-Weir 27-point-scale in Cox proportional hazards models.
J Prev Alzheimers Dis
February 2025
Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA; The Framingham Study, Framingham, MA, USA; Department of Neurology, Boston University School of Medicine, Boston, MA, USA.
Background: Ultra-processed food consumption is emerging as a risk factor for various cardiometabolic diseases, however its association with dementia and Alzheimer's disease has rarely been explored.
Objectives: We sought to examine whether ultra-processed food consumption is associated with risk of all-cause dementia and Alzheimer's disease among middle-age and older adults.
Design: A prospective cohort study.
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