AI Article Synopsis

  • The study aimed to establish reference values for major organ and tissue parameters in the Chinese Reference Man using samples from healthy adult males who had sudden deaths.
  • Researchers analyzed 18 major organs and collected blood samples from various provinces in China, utilizing advanced techniques to measure 56 different elemental concentrations.
  • The findings provided comprehensive data on elemental concentrations and their distribution in organs, enhancing the reliability of reference values for studying human health, particularly in relation to radiation protection.

Article Abstract

Objective: To provide basis of reference values for relevant parameters of Chinese Reference Man.

Methods: Eighteen kinds of major organ or tissue samples, including muscle, rib, liver, and so on, were obtained from 4 areas (Hebei, Shanxi, Jiangsu, and Sichuan provinces) with different dietary patterns in China in autopsy of 16 healthy adult men, who had just encountered sudden deaths. At the same time, whole blood samples were collected from 10 volunteers living in each of these areas. The concentrations of 56 elements in these samples were detected by using Inductively Coupled Plasma Mass Spectrometry (ICP-MS), Inductively Coupled Plasma Atomic Emission Spectrometry (ICP-AES), and Graphite Furnace Atomic Absorption Spectrometry (GF-AAS) techniques. Based on obtained concentrations and reference values of these organ or tissue weights for Chinese Reference Man, the relative elemental burdens in these organs or tissues as well whole body were also estimated.

Results: The concentrations of 56 elements in 18 main organs or tissues were determined all together and their elemental organ or tissue and whole body burdens were estimated. Furthermore, the distributions of important elements for radiation protection in these organs or tissues were emphatically discussed.

Conclusion: By summing with past related results, the total results obtained from the series of research may provide more reliable and better representative basis of these reference values for Chinese Reference Man than before.

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