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Cohort retention in a pandemic response study: lessons from the SARS-CoV2 Immunity & Reinfection Evaluation (SIREN) study.
BMC Med Res Methodol
January 2025
United Kingdom Health Security Agency (UKHSA), London, UK.
Background: SIREN is a healthcare worker cohort study aiming to determine COVID-19 incidence, duration of immunity and vaccine effectiveness across 135 NHS organisations in four UK nations. Conducting an intensive prospective cohort study during a pandemic was challenging. We designed an evolving retention programme, informed by emerging evidence on best practice.
View Article and Find Full Text PDFOptimized convolutional neural network using African vulture optimization algorithm for the detection of exons.
Sci Rep
January 2025
Department of Communication Engineering, School of Electronics Engineering, Vellore Institute of Technology, Vellore, Tamil Nadu, 632014, India.
The detection of exons is an important area of research in genomic sequence analysis. Many signal-processing methods have been established successfully for detecting the exons based on their periodicity property. However, some improvement is still required to increase the identification accuracy of exons.
View Article and Find Full Text PDFBalloon-mounted versus self-expandable stent in failed neurothrombectomy: a post hoc analysis of the SAINT study.
J Neurointerv Surg
January 2025
Department of Neurology, Emory University School of Medicine, Atlanta, Georgia, USA
Background: Previous studies have shown that when thrombectomy has failed, rescue intracranial stenting is associated with better clinical outcomes compared with failed reperfusion. However, comparative data regarding stent type are lacking.
Objective: To compare the procedural and clinical outcomes of balloon-mounted stents (BMS) with those of self-expandable stents (SES).
Outcomes of Patients Treated with Double-Wide Scallop vs Fenestrations for Celiac Artery Incorporation During Repair of Complex Abdominal Aortic Aneurysms.
J Vasc Surg
January 2025
Division of Vascular and Endovascular Surgery, Mayo Clinic, Rochester MN, USA. Electronic address:
Objectives: Celiac artery (CA) incorporation during FB-EVAR for complex abdominal aortic aneurysms (cAAA) is typically performed with fenestrations. Double-wide scallops (DWS) can be used when appropriate. We aimed to assess outcomes of patients treated with DWS for the CA during FB-EVAR for cAAA.
View Article and Find Full Text PDFMinimum initiatory concentration distribution of Mecillinam in clinical Staphylococcus saprophyticus isolates from Europe.
J Glob Antimicrob Resist
January 2025
Department of Clinical Microbiology, Rigshospitalet, Copenhagen, Denmark.
Background: Staphylococcus saprophyticus is the second most common bacteria causing uncomplicated urinary tract infections (UTI). It is considered non-susceptible to mecillinam, with no defined breakpoint and only few available minimal inhibitory concentration (MIC) observations. However, this consideration does not correlate with clinical outcome.
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