Idiopathic granulomatous mastitis is a rare inflammatory breast disease that mimics breast diseases such as inflammatory breast carcinoma, infective mastitis, and inflammatory breast disease of known cause. It is a diagnosis made only after excluding other causes, and although the disease is nonmalignant it may be both locally aggressive and recurrent. Definitive treatment may require radical excision and adjunctive treatment with immunosuppressants. Reconstruction following excision of disease has not been previously described. In those patients who undergo reconstruction, both the surgeon and the patient must be aware of complications associated with residual disease, and the potential involvement of donor sites. Treatment should be undertaken as part of a multidisciplinary team including surgeons and physicians with an interest in inflammatory breast disease. We present two patients diagnosed with idiopathic granulomatous mastitis who were referred to our unit for consideration of reconstruction. One patient underwent autologous breast reconstruction and the other contra lateral surgery to achieve symmetry.
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http://dx.doi.org/10.1111/j.1524-4741.2007.00474.x | DOI Listing |
Indian J Med Res
November 2024
Department of Receptor Biology and Tumor Metastasis, Chittaranjan National Cancer Institute, Kolkata, India.
Background & objectives The choice of anesthetic for better perioperative conservation of immune responses has always been contentious. This study investigated the differential impact of the intravenous anesthetic, propofol, and the volatile anesthetic, isoflurane on the T cell immune responses, if any, among individuals going through perioperative breast cancer. Methods Perioperative blood samples (preoperative, intraoperative and postoperative) collected from participants with breast cancer in two arms namely isoflurane arm (n=50) and the propofol arm (n=50) were analyzed for T cell immune response using flow cytometry and ELISA.
View Article and Find Full Text PDFJ Affect Disord
December 2024
Department of Breast Surgery, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang 310003, China. Electronic address:
Background: Few studies have explored the effects of arsenic exposure on depressive symptoms and the underlying mechanisms of its influence on this relationship. This study aimed to assess the impact of urinary arsenic on depressive symptoms and the mediating and moderating roles of folate and dietary inflammation index (DII).
Methods: Cross-sectional data from 9775 participants (≥20 years) in the National Health and Nutrition Examination Survey (NHANES) from 2005 to 2020 were used for analysis.
Front Vet Sci
December 2024
Institute of Animal Husbandry and Veterinary Science, Jiangxi Academy of Agricultural Sciences, Nanchang, China.
Turk J Med Sci
December 2024
Department of Pathology, Faculty of Veterinary Medicine, Bursa Uludağ University, Bursa, Turkiye.
Background/aim: Breast cancers are one of the most common cancers in women and are responsible for many deaths worldwide. Mast cells are inflammatory cells. Their role in cancers is controversial, and there is limited data on systemic mast cell activation in cancer cases.
View Article and Find Full Text PDFClin Breast Cancer
December 2024
Faculty of Medicine, Health and Life Science, Swansea University, Wales, United Kingdom.
Background: Adjuvant therapy decisions in hormone receptor positive, HER2 negative breast cancer are evolving. Gene panel testing has reduced the number of patients recommended for chemotherapy by up to two thirds. Identifying low risk genomic cases before testing could represent a significant economic impact.
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