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Impact of C-reactive protein levels on lipoprotein(a)-associated aortic stenosis incidence and progression.
Eur Heart J Open
March 2023
Centre de recherche de l'Institut universitaire de cardiologie et de pneumologie de Québec, Québec, QC, G1V 4G5, Canada.
Aims: Elevated lipoprotein(a) [Lp(a)] levels are associated with the risk of coronary artery disease (CAD) and calcific aortic valve stenosis (CAVS). Observational studies revealed that Lp(a) and C-reactive protein (CRP) levels, a biomarker of systemic inflammation, may jointly predict CAD risk. Whether Lp(a) and CRP levels also jointly predict CAVS incidence and progression is unknown.
View Article and Find Full Text PDFThe winter of raw computers: the history of the lunar and planetary reductions of the Royal Observatory, Greenwich.
Br J Hist Sci
March 2023
Royal Museums Greenwich, UK.
In 1839 the working hours of the computers employed on the lunar and planetary reductions of the Royal Observatory, Greenwich were reduced from eleven hours to eight hours. Previous historians have explained this decrease by reference to the generally benevolent nature of the manager of the reductions, George Biddell Airy. By contrast, this article uses the letters and notes exchanged between Airy and the computers to demonstrate that the change in the working hours originated from the computers as a reaction to their poor working conditions.
View Article and Find Full Text PDFGuidelines for the development of a critical software under emergency.
Inf Softw Technol
December 2022
AstroCeNT, N. Copernicus Astronomical Center, Polish Academy of Sciences, Warsaw, Poland.
Context: During the first wave of the COVID-19 pandemic, an international and heterogeneous team of scientists collaborated on a social project to produce a mechanical ventilator for intensive care units (MVM). MVM has been conceived to be produced and used also in poor countries: it is open-source, no patents, cheap, and can be produced with materials that are easy to retrieve.
Objective: The objective of this work is to extract from the experience of the MVM development and software certification a set of lessons learned and then guidelines that can help developers to produce safety-critical devices in similar emergency situations.
Detection of Airborne Inoculum of Hymenoscyphus fraxineus: The Causal Agent of Ash Dieback.
Methods Mol Biol
July 2022
Department of Forest Protection and Wildlife Management, Faculty of Forestry and Wood Technology, Mendel University in Brno, Brno, Czech Republic.
The inoculum of H. fraxineus consists mainly of ascospores released from apothecia which are growing on fallen leaves infected during the previous year. The ascospores can be detected in various manners due to their high concentration in the air during the main sporulation season, which corresponds to astronomic summer.
View Article and Find Full Text PDFA commentary of "Consistency radio bursts in the Milky Way": 10 remarkable discoveries from 2020 in .
Fundam Res
March 2022
National Astronomical Observatories, Chinese Academy of Sciences, Beijing, 100101, China.
The first detection and deep follow-up of a Galactic fast radio burst (FRB) phenomenon were reported in three papers published in the journal in November 2020. Interestingly, this FRB is accompanied by a X-ray burst. The observations from multiple space and ground-based telescopes were combined to accomplish this discovery and ascertain its association with a source in the Milky Way.
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