AI Article Synopsis

  • The study aimed to establish a method for measuring herberine levels in different Maxingganshi decoction combinations using HPLC and evaluate how these combinations affect overall content.
  • By using a specific experimental design, researchers found that removing certain ingredients (Glycyrrhiza uralensis and armeniacae semen) significantly altered the levels of various compounds, such as L-ephedrine and glycyrrhetic acid.
  • The results indicate that armeniacae semen reduces L-ephedrine and D-pseudephedrine levels, while Glycyrrhiza uralensis enhances the extraction of useful compounds like amygdaloside and glycyrrhizic acid.

Article Abstract

Objective: To set up the quantitative method of herberine in decoctions prepared from various combinations of Maxingganshi decotion by HPLC and to determine the change of general contents in different decoction.

Methods: The study was designed by L8 (2(7)) orthogonal and to determine the change of general contents in different decoction by HPLC.

Results: In full formula remove Glycyrrhiza uralensis group, the contents of L-ephedrine, d-pseudephedrine and the amygdaloside cut down significantly. In full formula remove armeniacae semen group, the content of glycyrrhetic acid cut down significantly. Four chemical composition in full formula group had higher contents.

Conclusion: Armeniacae semen can decrease the content of L-ephedrine, D-pseudephedrine. Glycyrrhiza uralensis can help decoctum amygdaloside and armeniacae semen can help decoctum glycyrrhizic acid.

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