Recurrent liver metastases of colorectal carcinoma are frequent. The repeat hepatectomy is superior to other therapeutic options. In about 20% of patients with recurrent liver metastases a complete resection (R0) is possible. The morbidity of repeat hepatectomy is similar to that of first hepatectomy. The 5-year survival rate after repeat hepatectomy ranges between 30 and 40%. Often in the follow-up additional operations become necessary for extrahepatic recurrencies. For determination of the optimal therapy an interdisciplinary approach must be chosen.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1055/s-2007-981196 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Initial experience of parenchyma-sparing liver resection with systematic selective hepatic vein reconstruction for colorectal metastases.
BMJ Surg Interv Health Technol
December 2024
Bogomolets National Medical University, Kiiv, Ukraine.
Objectives: This study aims to assess the feasibility and short-term and intermediate-term technical success rate of the concept of systematic selective hepatic vein (HV) reconstruction for parenchyma-sparing hepatectomies (PSHs) in patients with colorectal liver metastases (CRLM) in accordance with stage 2a of the IDEAL framework.
Design: The prospective case series of patients deemed eligible and operated on according to the concept.
Setting: All patients were treated by a single surgical team in three hospitals in Ukraine from June 2022 to November 2023.
Treatment-sequencing before and after index hepatectomy with either synchronous or metachronous colorectal liver metastasis: Comparison of recurrence risk, repeat hepatectomy and overall survival in a population-derived cohort.
Eur J Surg Oncol
December 2024
Department of Gastrointestinal Surgery, Stavanger University Hospital, Stavanger, Norway; Gastrointestinal Translational Research Group, Laboratory for Molecular Medicine, Stavanger University Hospital, Stavanger, Norway; Department of Clinical Medicine, University of Bergen, Bergen, Norway. Electronic address:
Background: Treatment of colorectal cancer liver metastasis (CRLM) includes several options with impact on the patient journey and may depend on presentation and patient characteristics. The aim of the study was to investigate how treatment sequencing in index hepatectomy for synchronous or metachronous CRLM may potentially impact treatment pathways and oncological outcomes.
Methods: An observational cohort study (ACROBATICC; NCT0176813) of patients having surgery for CRLM.
Evaluation of Postoperative Adhesions in a Subsequent Cesarean Section Following the Use of Dextrin Hydrogel Spray as Adhesion Barrier for Laparoscopic Myomectomy.
Gynecol Minim Invasive Ther
October 2024
Department of Obstetrics and Gynecology, Teine Keijinkai Hospital, Sapporo, Japan.
Objectives: Laparoscopic myomectomy (LM) is a procedure with a high rate of postoperative adhesions, which can lead to complications such as bowel obstruction and subsequent surgical problems, making anti-adhesion measures important. Various anti-adhesion materials are already on the market and have shown efficacy, but dextrin hydrogel spray (AdSpray™), an anti-adhesion material launched in 2017, has not yet been reported in the field of gynecology, although there are papers showing its usefulness in the surgical field such as repeat hepatectomy and ileostomy closure. Thereby, we investigated the postoperative status of AdSpray™ in LM.
View Article and Find Full Text PDFRepeat laparoscopic hepatectomy versus radiofrequency ablation for recurrent hepatocellular carcinoma: A multicenter, propensity score matching analysis.
Biosci Trends
December 2024
Department of Hepatic Surgery VI, Eastern Hepatobiliary Surgery Hospital, The Third Affiliated Hospital of Naval Military Medical University, Shanghai, China.
Article Synopsis
- This study compares the effectiveness of repeat laparoscopic hepatectomy (r-LH) and radiofrequency ablation (RFA) in treating patients with recurrent hepatocellular carcinoma (RHCC) based on clinical outcomes and survival rates.
- Data from 272 RHCC patients were analyzed, revealing that while RFA resulted in shorter hospital stays and fewer complications, r-LH significantly improved overall and disease-free survival rates.
- Particularly, patients with solitary tumors or those located near critical structures benefitted more from r-LH, especially when tumors were 5 cm or smaller, suggesting it as a more favorable treatment option in these cases.
Strategies for Recurrent Colorectal Liver Metastases Based on Prognostic Factors and Resectability: Potential Benefit of Multidisciplinary Treatment.
Ann Surg Oncol
November 2024
Division of Hepatobiliary and Pancreatic Surgery, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Tokyo, Japan.
Background: Colorectal liver metastasis (CLM) is classified into technical and oncologic categories, with recommended treatments for each resectability category. However, the classification of recurrent CLM has not been established to date.
Methods: This study evaluated patients with CLM who underwent initial liver resection between 2006 and 2020 and subsequently experienced liver recurrence.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!