Objective: To analyze the time course of caloric response in patients with Benign Paroxysmal Positional Vertigo (BPPV).
Patients: Seventy-four individuals with diagnosis of BPPV during Dix-Hallpike (DH) test.
Study Design: A prospective, longitudinal study.
Setting: A tertiary referral center.
Intervention: Patients were treated by particle repositioning maneuvers according to the affected canal, and the effectiveness was evaluated at 180 and 360 days. Bithermal caloric response was obtained by using 44 and 30 degrees C water irrigations at diagnosis, 6 months, and 1 year after.
Main Outcome Measure: Canal paresis (CP) and response to DH after treatment.
Results: The effectiveness of the treatment for BPPV (absence of vertigo and positional nystagmus during DH) was 65.2% (45 of 69) after 1 year of follow-up. Twenty-five percent of (16 of 64) individuals with BPPV presented CP at diagnosis, 27% (12 of 44) at 6 months, and 16% (9 of 56) 1 year after. One year after, seven individuals with CP showed a normal caloric response, another seven demonstrated persistent CP, and one case developed a bilateral CP. The effectiveness of particle repositioning maneuvers was not significantly different between subjects with or without CP after 1 year of follow-up (odds ratio, 1.31 [95% confidence intervals, 0.35-4.89], p = 0.88).
Conclusion: Canal paresis is not associated with a lower outcome to repositioning.
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http://dx.doi.org/10.1097/MAO.0b013e318067e322 | DOI Listing |
Sci Rep
January 2025
Department of Biological Sciences, University of Southern California, 3616 Trousdale Parkway, AHF 252, Los Angeles, CA, 90089-0372, USA.
Habitual consumption of low-calorie sweeteners (LCS) during juvenile-adolescence can lead to greater sugar intake later in life. Here, we investigated if exposure to the LCS Acesulfame Potassium (Ace-K) during this critical period of development reprograms the taste system in a way that would alter hedonic responding for common dietary compounds. Results revealed that early-life LCS intake not only enhanced the avidity for a caloric sugar (fructose) when rats were in a state of caloric need, it increased acceptance of a bitterant (quinine) in Ace-K-exposed rats tested when middle-aged.
View Article and Find Full Text PDFPhysiol Rev
January 2025
University of Zurich, Vetsuise Faculty, Institute of Veterinary Physiology, Zurich, Switzerland.
Metabolic energy stored mainly as adipose tissue is homeostatically regulated. There is strong evidence that human body weight () is physiologically regulated, i.e.
View Article and Find Full Text PDFEndocrinology
January 2025
Department of Pediatrics, Divisions of Neonatology & Developmental Biology and Endocrinology, Neonatal Research Center of the UCLA Children's Discovery & Innovation Institute at the David Geffen School of Medicine at UCLA, Los Angeles, California 90095-1752.
To determine the basis for perinatal nutritional mismatch causing metabolic dysfunction associated steatotic liver disease (MASLD) and diabetes mellitus, we examined adult phenotype, hepatic transcriptome, and pancreatic β-islet function. In prenatal caloric restricted rat with intrauterine growth restriction (IUGR) and postnatal exposure to high fat with fructose (HFhf) or high carbohydrate (RC), we investigated male and female IUGR-Hfhf and IUGR-RC, versus HFhf and CON offspring. Males more than females displayed adiposity, glucose intolerance, insulin resistance, hyperlipidemia, hepatomegaly with hepatic steatosis.
View Article and Find Full Text PDFPLoS One
January 2025
Faculty of Natural Sciences, Department of Molecular Biology, Ariel University, Ariel, Israel.
Objectives: Epithelial ovarian cancer is a significant contributor to cancer-related mortality in women, frequently recurring post-treatment, often accompanied by chemotherapy resistance. Dietary interventions have demonstrated influence on cancer progression; for instance, caloric restriction has exhibited tumor growth reduction and enhanced survival in animal cancer models. In this study, we calculated a transcriptomic signature based on caloric-restriction for ovarian cancer patients and explored its correlation with ovarian cancer progression.
View Article and Find Full Text PDFCyberpsychol Behav Soc Netw
January 2025
Department of Communication, University of Delaware, Newark, Delaware, USA.
Smartwatches are digital devices, similar to smartphones, and come with the possibility of problematic use. Problematic technology use is the experience of psychological distress or reduced daily functioning in response to excessive or addictive technology use. The purpose of this study was to explore whether problematic use of smartwatch devices for exercise tracking influences user's health behaviors such as eating habits and sedentary activity.
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