AI Article Synopsis
- Kaposi's sarcoma (KS) is a type of cancer linked to human herpesvirus 8, typically showing up as skin lesions but can occur in lymph nodes.
- A 28-year-old man experienced enlarged lymph nodes with no other health issues, leading to a diagnosis of KS after a fine needle aspiration and subsequent lymph node removal.
- The case highlights that KS in lymph nodes can be an early indicator of HIV infection, even when no other symptoms are present.
Article Abstract
Background: Kaposi's sarcoma (KS) is a vascular malignant tumor characterized by human herpesvirus 8 infection of neoplastic cells. Diffuse cutaneous lesions represent the classical clinical presentation. This case report describes the first fine needle aspiration cytology findings of a primary lymph nodal KS, a rather unusual localization of the disease.
Case: A 28-year-old, apparently healthy man saw a surgeon for right inguinal node enlargement without other symptoms. The clinician performed fine needle aspiration and made a preliminary diagnosis of a neoplasm of probable mesenchymal origin, not otherwise specified. The lymph node was excised, and the final histologic diagnosis was primary lymphoadenopathic KS. A serologic test revealed antibody positivity for HIV.
Conclusion: The diagnosis of primary KS of the lymph node, in the absence of any other clinical manifestation, was the first sign of HIV infection.
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| http://dx.doi.org/10.1159/000325807 | DOI Listing |
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