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Neuropsychiatric Outcomes in Children and Adolescents with Perinatally Acquired HIV: A Systematic Review and Meta Analysis.
J Acquir Immune Defic Syndr
January 2025
Department of Psychiatry, University of Oxford, Oxford OX3 7JX, UK.
Objective: The objective of this study is to define the neuropsychiatric challenges including developmental delay, cognitive impairment and psychiatric illness faced by children with perinatally acquired HIV.
Data Sources: Nine databases were searched on 30/05/2023: MEDLINE, Embase, and PsycINFO (all via Ovid SP); CINAHL and Child Development and Adolescent Studies (via EBSCO); the Web of Science Core Collection; Scopus; ProQuest Dissertations and Theses Global; and WHO Global Index Medicus. No limits were applied.
How People With Vision Impairment Use Their Gaze to Hit a Ball.
Transl Vis Sci Technol
January 2025
Vrije Universiteit Amsterdam, Department of Human Movement Sciences, Amsterdam Movement Sciences and Institute Brain and Behaviour Amsterdam (iBBA), Amsterdam, the Netherlands.
Purpose: Understanding the impact of vision impairment on dynamic tasks requiring visual processing is crucial for developing effective adaptive strategies that support individuals with vision impairment in optimizing their performance in natural tasks. This study aimed to establish the gaze patterns used by individuals with vision impairment when hitting a moving target.
Methods: Nineteen tennis players with vision impairment were recruited and their eye and head movements were tracked while they returned tennis serves.
Retinal Müller Cell-Released Exosomal MiR-92a-3p Delivers Interleukin-17A Signal by Targeting Notch-1 to Promote Diabetic Retinopathy.
Invest Ophthalmol Vis Sci
January 2025
Department of Ophthalmology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Purpose: Inflammatory processes have been involved in diabetic retinopathy (DR). Interleukin (IL)-17A, a pro-inflammatory cytokine, is associated with DR occurrence and development. However, mechanisms underlying the IL-17A impact on DR need further investigations.
View Article and Find Full Text PDFImplementing brief behavioral treatment for insomnia in Department of Veterans Affairs Primary Care Mental Health Integration clinics: Reach outcomes from a hybrid type 3 effectiveness-implementation trial.
Psychol Serv
January 2025
Center for Health Equity Research and Promotion, Department of Veterans Affairs Pittsburgh Healthcare System.
Chronic insomnia is one of the most common health problems among veterans and can significantly impact health, function, and quality of life. Brief behavioral treatment for insomnia (BBTI), an adaptation of cognitive behavioral therapy for insomnia (CBT-I), was developed to help increase access to care outside of specialty settings. However, training providers alone is rarely sufficient, and implementation strategies are needed for successful uptake, adoption, and sustainable delivery of care.
View Article and Find Full Text PDFLINNAEUS: Simultaneous Single-Cell Lineage Tracing and Cell Type Identification.
Methods Mol Biol
January 2025
Charité Universitätsmedizin Berlin, Berlin, Germany.
A key goal of biology is to understand the origin of the many cell types that can be observed during diverse processes such as development, regeneration, and disease. Single-cell RNA-sequencing (scRNA-seq) is commonly used to identify cell types in a tissue or organ. However, organizing the resulting taxonomy of cell types into lineage trees to understand the origins of cell states and relationships between cells remains challenging.
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