Adducts of uridine and glycals as potential substrates for glycosyltransferases.

Bioorg Chem

Silesian University of Technology, Faculty of Chemistry, Department of Organic Chemistry, Bioorganic Chemistry and Biotechnology, 44-100 Gliwice, Krzywoustego 4, Poland.

Published: October 2007

We report on the synthesis of 2-deoxyglycosyl derivatives of uridine as potential donor substrates for glycosyltransferases. The totally stereoselective synthesis is accomplished by two sequential addition reactions of uridine derivatives to glycals promoted by triphenylphosphine-hydrogen bromide.

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Source
http://dx.doi.org/10.1016/j.bioorg.2007.07.001DOI Listing

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