Three experimental self-etching primers - consisting of N-methacryloyl-omega-aminoalkyl phosphonic acid (NMomegaP) with different methylene chain lengths and N-methacryloyl glycine (NMGly) - were formulated. The influence of methylene chain length in NMomegaP derivatives on the chemical nature of calcium salts was examined following their application to tooth components. Bond strengths of experimental self-etching primers created with these monomers to enamel and dentin were also investigated. Nuclear magnetic resonance spectroscopy showed that NMomegaPs decalcified tooth components with formation of calcium salts, which changed from calcium hydrogen phosphonate to calcium phosphonate with increase in methylene chain length within the NMomegaP structure. Disparity in calcium salt formation was related to increases in bond strength to enamel from 18 to 24 MPa. However, bond strength to dentin remained unchanged (22 MPa). The relative dependency of bond strength on monomer methylene chain length was probably attributable to the sites where these NMomegaP calcium salts had deposited on the bonding substrates.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.4012/dmj.26.382 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
The Unusual Mesophases and Properties Exhibited by a Family of Glycosteroids.
Chemistry
January 2025
Universite Claude Bernard Lyon 1, ICBMS, Bâtiment Lederer, 1 Rue Victor Grignard, F-69622, Villeurbanne, FRANCE.
In this article we describe research on the synthesis and characterization of a family of "Janus" amphiphiles composed of disaccharide head groups and alkaloid units joined together via a methylene linker, and bearing a lateral aliphatic chain of varying length. The condensed phases formed by self-organization of the products as a function of temperature were characterized by differential scanning calorimetry, thermal polarized light microscopy, and small angle X-ray scattering, allied with computational modelling and simulations. Structural studies on heating specimens from the solid showed that some homologues exhibited lamellar, columnar and bicontinuous mesophases, whereas the same homologues revealed different phase sequences on cooling from the amorphous liquid.
View Article and Find Full Text PDFGenetically Predicted Gut Microbiota Mediate the Association Between Fatty Acids and Intrahepatic Cholestasis of Pregnancy: A Mendelian Randomization Analysis.
Food Sci Nutr
January 2025
Affiliated Women's Hospital of Jiangnan University, Jiangnan University Wuxi China.
Fatty acids (FAs) and gut bacteria likely play vital roles in intrahepatic cholestasis of pregnancy (ICP). However, the causal connection between FAs, gut microbiota, and ICP has not yet been confirmed. To investigate the associations of FAs, gut bacteria, and ICP, a Mendelian randomization (MR) analysis with two samples was performed to identify the potential causal relationships between FAs and ICP.
View Article and Find Full Text PDFFrom Molecular to Radionuclide and Pharmacological Aspects in Transthyretin Cardiac Amyloidosis.
Int J Mol Sci
December 2024
Clinic of Nuclear Medicine Central University Emergency Military Hospital "Dr Carol Davila", 10825 Bucharest, Romania.
Amyloidosis is a rare pathology characterized by protein deposits in various organs and tissues. Cardiac amyloidosis (CA) can be caused by various protein deposits, but transthyretin amyloidosis (ATTR) and immunoglobulin light chain (AL) are the most frequent pathologies. Protein misfolding can be induced by several factors such as oxidative stress, genetic mutations, aging, chronic inflammation, and neoplastic disorders.
View Article and Find Full Text PDFDetection of microRNA-21 based on smartly designed ratiometric electrochemical sensor and dual-signal amplification.
Anal Chim Acta
January 2025
Shandong Provincial Key Laboratory of Detection Technology for Tumor Markers, School of Medicine, Linyi University, Linyi, China. Electronic address:
MicroRNA (miRNA) serves as an effective and viable biomarker for early diagnosis and monitoring of cancer disorders. It is highly expressed in tumor cells, including lung cancer, liver cancer and lymphoma. Herein, we propose a ratiometric electrochemical sensor for ultrasensitive detection of miRNA-21 using dual signal amplification, hybridization chain reaction and Exo III assisted-amplification.
View Article and Find Full Text PDFDual-mode ultrasensitive detection of acute leukemia gene Pax-5a based on smart DNA programmed dendrimer.
Biosens Bioelectron
December 2024
State Key Laboratory for Chemo/Biosensing and Chemometrics, Hunan University, Changsha, 410082, PR China.
Accurate and sensitive detection of Pax-5a gene is the basis of early diagnosis and prediction of acute leukemia. This research aims to develop a universal dual-mode sensing method enables ultrasensitive gene detection based on smart control of DNA amplification by nucleic acid beacons e to form programmed dendrimer. The Pax-5a target gene triggers the opening of smart gate hairpin probe (Hp), exposing the stem sequence as the primer to bind with padlock probe for rolling circle amplification (RCA).
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!