Prinzmetal's angina is a condition characterized by chest pain, transient ST elevation, and negative biochemical markers of myocardial cell necrosis. We describe a case of chemically-induced "silent" ST segment elevation related to Atenolol overdose in a patient without coronary artery stenosis. We conclude that the cause for the transient myocardial ischemia is coronary vasospasm, precipitated by beta-blocker overdose.
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http://dx.doi.org/10.1016/j.jemermed.2007.02.028 | DOI Listing |
Blood Press Monit
November 2024
Department of Cardiovascular Medicine, Centre for Epidemiological Studies and Clinical Trials, State Key Laboratory of Medical Genomics, Shanghai Key Laboratory of Hypertension, Shanghai Institute of Hypertension, National Research Centre for Translational Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Objective: The objective of this study was to investigate the efficacy of the nitrendipine/atenolol combination in comparison with standard-dose nitrendipine or atenolol monotherapy in reducing blood pressure (BP) and blood pressure variability (BPV) as assessed by ambulatory BP monitoring.
Methods: In a randomized, crossover trial, 32 patients (30-65 years) with grade 1 hypertension and elevated daytime reading-to-reading BPV were randomly assigned to receive either the nitrendipine/atenolol combination (10/20 mg) or standard-dose nitrendipine (10 mg) or atenolol (25 mg) monotherapy for 6 weeks, followed by a crossover to another treatment for 6 weeks.
Results: The final analysis included 31 patients (mean [±SD] age, 49.
Cureus
October 2024
Obstetrics and Gynaecology, An-Najah National University, Nablus, PSE.
Long QT syndrome (LQTS) presents significant challenges for pregnant women due to the elevated risk of arrhythmic events. Beta-blocker therapy is a cornerstone of treatment in managing LQTS, but its use during pregnancy introduces potential fetal risks. This systematic review synthesizes the evidence on the efficacy and safety of beta-blocker therapy in pregnant women with LQTS.
View Article and Find Full Text PDFJ Perinat Med
October 2024
Department of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine, College of Medicine - Tucson, University of Arizona, Tucson, AZ, USA.
Objectives: Atenolol is a commonly used beta bloscker in non-pregnant women. Many providers are hesitant in prescribing atenolol in pregnancy because of a possible association with poor fetal growth. We aimed to assess the association between atenolol and the occurrence of small for gestational age neonates compared to other beta blockers, as described in the existing literature.
View Article and Find Full Text PDFPediatrics
September 2024
Department of Pediatrics, Guerin Children's at Cedars-Sinai Medical Center, Los Angeles, California.
J Vet Cardiol
August 2024
Department of Clinical Science and Services, The Royal Veterinary College, Hawkshead Ln, Brookmans Park, Hatfield AL9 7TA, United Kingdom.
Three cats were presented for unusual collapsing episodes. Echocardiography revealed a hypertrophic cardiomyopathy (HCM) phenotype in each cat. Continuous electrocardiographic monitoring showed that the clinical signs coincided with periods of severe ST-segment elevation in each cat.
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