The aim of this review is precisely to give a comprehensive account of the large volume of work carried out on 1,4-diazepines regardless of the degree of unsaturation in the diazepine system. This review mainly emphasizes recent work on the diazepines also including earlier work.
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Conservation challenges for Brazilian primates and the role of protected areas in a changing climate.
Sci Rep
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Programa de Pós-Graduação em Ecologia, Instituto de Ciência Biológicas, Universidade Federal do Pará, Belém, Brazil.
The negative effects of land-use changes on biodiversity significantly contribute to climate change. Primates are among the animals most affected by these changes, because of their high dependence on forest cover where a lack of forest connectivity can limit their dispersal and segregate their populations. In this sense, protected areas (PAs) are crucial for conserving endangered primates, especially endemic species.
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Fundación Elena Barraquer, Barcelona, Spain; Qvision, VITHAS Hospital, Almería, Spain.
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View Article and Find Full Text PDFUnified Knowledge-Guided Molecular Graph Encoder with multimodal fusion and multi-task learning.
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School of Computer Science, Wuhan University, Luojiashan Road, Wuchang District., Wuhan, 430072, Hubei Province, China; Hubei Key Laboratory of Digital Finance Innovation, Hubei University of Economics, No. 8, Yangqiaohu Avenue, Zanglong Island Development Zone, Jiangxia District, Wuhan, 2007, Hubei Province, China. Electronic address:
The remarkable success of Graph Neural Networks underscores their formidable capacity to assimilate multimodal inputs, markedly enhancing performance across a broad spectrum of domains. In the context of molecular modeling, considerable efforts have been made to enrich molecular representations by integrating data from diverse aspects. Nevertheless, current methodologies frequently compartmentalize geometric and semantic components, resulting in a fragmented approach that impairs the holistic integration of molecular attributes.
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Department of Clinical Epidemiology and Health Economics, School of Public Health, The University of Tokyo, Tokyo, Japan.
Objective: In Japan, the current coverage rate of human papillomavirus (HPV) vaccination is only 30%, and the rate of biennial cervical screening is 40%. The Japanese Government has attempted to increase the coverage of HPV vaccination and cervical screening. We analyzed the cost-effectiveness of the 9-valent HPV vaccine and cervical screening in Japan.
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Western Sydney University, School of Computer, Data and Mathematical Sciences, Sydney, Australia.
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