This study presents an examination on the correlation of sonication operating condition, sludge property, formation and behaviour of cavitation bubbles in sludge disruption under low-frequency ultrasound sonication. The influence of sonication time, sonication density, type of sludge and solids content on the disruption was evaluated. The most vigorous particle disruption was achieved in the initial period of sonication, which subsided subsequently. The explosive effect was likely due to the rapid cavitation arising from powerful transient bubbles generated in fractions of microseconds. A rating for the type of sludge was derived based on the finding that particles in secondary sludge were more readily disrupted than both primary sludge and mixed sludge. While sonication density exhibited the most significant role in cavitation bubble formation and behaviour, particle disruption could be optimised for energy input by sonicating at higher sonication density and shorter sonication time. Based on theoretical consideration, it was deduced that within an optimum sludge solids content ranging between 2.3% and 3.2%, superior particle disruption could be accomplished within a minute for secondary sludge sonicated at a density of 0.52 W/mL. Useful guidelines for sonication system installation, equipment protection and process reliability could be established from knowledge derived from a good understanding on the influence of solids content on sludge sonication.
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http://dx.doi.org/10.1016/j.watres.2007.07.017 | DOI Listing |
J Hepatol
January 2025
MASLD Research Center, Division of Gastroenterology and Hepatology, University of California at San Diego, La Jolla, CA, USA.
Background & Aims: A common genetic variant (rs738409) encoding isoleucine to methionine at position 148 in the PNPLA3 protein is a determinant of hepatic steatosis, inflammation, fibrosis, cirrhosis, and liver-related mortality. AZD2693 is a liver-targeted antisense oligonucleotide against PNPLA3 mRNA. We evaluated the safety, tolerability, pharmacokinetics, and pharmacodynamics in single ascending dose (SAD) and multiple ascending dose (MAD) studies.
View Article and Find Full Text PDFTransgenic Res
January 2025
Plant Transgenic Laboratory, CSIR-National Botanical Research Institute, Rana Pratap Marg, Uttar Pradesh, Lucknow, 226001, India.
This study aimed to develop a reliable and efficient genetic transformation method for the ornamental Indian Lotus (Nelumbo nucifera Gaertn.) using the sonication-assisted Rhizobium radiobacter-mediated transformation technique. To conduct the transformation, shoot apical meristem explants were infected with Rhizobium radiobacter (synonym Agrobacterium tumefaciens) strain LBA 4404 containing a binary vector pBI121 that harbours the GUS reporter gene (uidA) and kanamycin resistance gene nptII for plant selection.
View Article and Find Full Text PDFFoods
December 2024
Department of Food Technology, Faculty of Kadirli Applied Sciences, Osmaniye Korkut Ata University, 80760 Kadirli, Osmaniye, Turkey.
The present study aimed to evaluate the antibiofilm effect of combined sonication treatment with organic acids on polystyrene surfaces and to develop a predictive model for the inactivation of biofilms. Polystyrene plates containing biofilms were subjected to sonication using different inactivation solutions (PBS, lactic acid, and acetic acid) at varying temperatures (20 °C, 40 °C, and 50 °C) and durations (2 and 5 min). The effects of temperature, treatment duration, and inactivation solution on biofilm removal were statistically significant ( < 0.
View Article and Find Full Text PDFFront Pharmacol
December 2024
Institute of Basic Medical Sciences of Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing Key Laboratory of Chinese Materia Pharmacology, National Clinical Research Center of Traditional Chinese Medicine for Cardiovascular Diseases, Beijing, China.
Introduction: Ischemic stroke greatly threatens human life and health. Neuro-restoration is considered to be the critical points in reestablishing neurological function and improving the quality of life of patients. Catalpol is the main active ingredient of the Chinese herbal medicine , which has the beneficial efficacy in traditional remedy, is closely related to the mitochondrial morphology and function.
View Article and Find Full Text PDFBoundary Layer Meteorol
April 2024
Department of Civil and Environmental Engineering, University of California, Irvine, CA 92697 USA.
Wildland fire-atmosphere interaction generates complex turbulence patterns, organized across multiple scales, which inform fire-spread behaviour, firebrand transport, and smoke dispersion. Here, we utilize wavelet-based techniques to explore the characteristic temporal scales associated with coherent patterns in the measured temperature and the turbulent fluxes during a prescribed wind-driven (heading) surface fire beneath a forest canopy. We use temperature and velocity measurements from tower-mounted sonic anemometers at multiple heights.
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