Embryos of the Sea Urchin Paracentrotus lividus were incubated for different periods of time in various concentrations of Zinc-ethylenebisdithiocarbamate (ZINEB) in artificial (or natural) sea water. Dramatic developmental modifications have been observed after 48 hour treatment with 0.4 ug/ml ZINEB solution. The abnormalities concern the formation of spiculae.
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PLoS One
December 2024
Faculty of Science, Department of Zoology, Alexandria University, Alexandria, Egypt.
The present study investigates the neuroprotective effects of the sea urchin Paracentrotus lividus gonadal extract on rotenone-induced neurotoxicity in a Parkinson's disease (PD) rat model. Parkinson's disease, characterized by the progressive loss of dopaminergic neurons in the substantia nigra (SN), is exacerbated by oxidative stress and neuroinflammation. The study involved fifty Wistar rats divided into five groups: control, dimethyl sulfoxide (DMSO) control, Paracentrotus lividus gonadal extract-treated, rotenone-treated, and combined rotenone with Paracentrotus lividus gonadal extract-treated.
View Article and Find Full Text PDFJ Hazard Mater
December 2024
Institute of Translational Pharmacology (IFT), National Research Council (CNR), Via Ugo La Malfa 153, Palermo 90146, Italy. Electronic address:
The innate immune system is the first player involved in the recognition/interaction with nanomaterials. Still, it is not the only system involved. The co-evolution of the microbiota with the innate immune system built an interdependence regulating immune homeostasis that is poorly studied.
View Article and Find Full Text PDFJ Hazard Mater
February 2025
EOMAR, ECOAQUA, Universidad de Las Palmas de Gran Canaria, Canary Islands, Spain. Electronic address:
J Biomol Struct Dyn
November 2024
Faculty of Science, Department of Biology, Molecular Biology Section, Ege University, Izmir, Türkiye.
PLoS Biol
November 2024
Sorbonne Université, CNRS, Institut de la Mer de Villefranche (IMEV), Laboratoire de Biologie du Développement de Villefranche-sur-Mer (LBDV), Evolution of Intercellular Signaling in Development (EvoInSiDe), Villefranche-sur-Mer, France.
Establishment of the 3 primordial germ layers (ectoderm, endoderm, and mesoderm) during early animal development represents an essential prerequisite for the emergence of properly patterned embryos. β-catenin is an ancient protein that is known to play essential roles in this process. However, these roles have chiefly been established through inhibition of β-catenin translation or function at the time of fertilization.
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