Online haemodiafiltration is an extracorporeal technique, utilizing highly permeable and highly biocompatible membranes, which permits the combination of convective and diffusive solute removal from the blood and offers increased removal of medium-weight uraemic solutes, compared to the more frequently used low-and high-flux haemodialysis. The objective of this chapter is to review the membranes and filters available for haemodiafiltration and to discuss factors that influence their performance during clinical use.
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http://dx.doi.org/10.1159/000107235 | DOI Listing |
Macromol Rapid Commun
December 2024
Empa, Swiss Federal Laboratories for Materials Science and Technology, Laboratory for Biomimetic Membranes and Textiles, St. Gallen, 9014, Switzerland.
Facemask materials have been under constant development to optimize filtration performance, wear comfort, and general resilience to chemical and mechanical stress. While single-use polypropylene meltblown membranes are the established go-to material for high-performing mask filters, they are neither sustainable nor particularly resistant to sterilization methods. Herein an in-depth analysis is provided of the sterilization efficiency, filtration efficiency, and breathing resistance of selected aerosol filters commonly implemented in facemasks, with a particular focus on the benefits of nanofibrous filters.
View Article and Find Full Text PDFNanomaterials (Basel)
December 2024
Departament de Ciència de Materials i Química Física, Institut de Química Teòrica i Computacional (IQTCUB), Universitat de Barcelona, C/Martí i Franquès 1-11, 08028 Barcelona, Spain.
The separation of oxygen (O) and nitrogen (N) from air is a process of utmost importance nowadays, as both species are vital for numerous fundamental processes essential for our development. Membranes designed for their selective molecule separation have become the materials of choice for researchers, primarily due to their ease of use. The present study proposes grazynes, 2D carbon-based materials consisting of and C atoms, as suitable membranes for separating O and N from air.
View Article and Find Full Text PDFFront Immunol
December 2024
Institute of Clinical Molecular Biology, University Hospital Schleswig-Holstein (UKSH) and Christian-Albrechts-University of Kiel, Kiel, Germany.
Kell is one of the most complex blood group systems, with a highly polymorphic genetic background. Extensive allelic variations in the gene affect the encoded erythrocyte surface protein Kell. Genetic variants causing aberrant splicing, premature termination of protein translation, or specific amino acid exchanges lead to a variety of different phenotypes with altered Kell expression levels or changes in the antigenic properties of the Kell protein.
View Article and Find Full Text PDFPDA J Pharm Sci Technol
December 2024
Meissner Corporation.
FDA recommends monitoring differential pressure across filter membranes during sterile filtration process validation. However, few resources are available to help pharmaceutical manufacturers anticipate expected differential pressures during sterilizing filtration of different solutions. To address this gap, Meissner evaluated differential pressures across different filtration membranes using various test solutions at increasing pump speeds.
View Article and Find Full Text PDFInt J Biol Macromol
December 2024
Post-Graduation Program in Materials Sciences (PPGCM), Federal University of São Carlos (UFSCar), 18052-780, Brazil; Laboratory of Biomaterials, Faculty of Medical Sciences and Health (FCMS), Pontifical Catholic University of São Paulo (PUC-SP), 18030-070, Brazil; Mechanical Engineering Faculty (FEM), State University of Campinas (UNICAMP), 13083-970, Brazil; Post-Graduation Program of Biomaterials and Regenerative Medicine (PPGBMR), Surgery Department, (PUC-SP), 18030-070, Brazil.
Wound healing is a complex process involving a sequence of factors that can be disrupted, negatively impacting the quality of life for patients and overburdening healthcare systems. Advanced dressings obtained by electrospinning are highlighted by the optimization of this process, allowing air exchange and protection against microorganisms. Aiming to develop bioactive dressings, this study investigated the physicochemical, mechanical, microbiological, and in vitro biological properties of membranes containing 25 %, 50 %, 75 %, and 90 % copaiba oil (CO) co-electrospun with poly(L-co-D,L-lactic acid) (PLDLA) and natural rubber latex (NR).
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