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[Pre-implementation of electronic patient-reported outcomes at reference centers for head and neck oncology : A roadmap towards patient-centered digitalization].
HNO
January 2025
Universitätsklinik für Hals‑, Nasen- und Ohrenheilkunde, Kopf- und Halschirurgie Innsbruck, Medizinische Universität Innsbruck, Anichstr. 35, 6020, Innsbruck, Österreich.
Background: Electronically captured patient reports (electronic patient-reported outcomes, ePROs) are digital questionnaires filled out by cancer patients. Despite indications of improved clinical care, the integration of ePROs into clinical head and neck oncology is uncharted territory.
Objective: This work outlines the implementation process for ePROs at the University Hospital for Otorhinolaryngology at the Medical University of Innsbruck (ENT Innsbruck).
Whole-exome sequencing identifies novel mutation in intrahepatic cholestasis of pregnancy: A case report and literature review.
Z Geburtshilfe Neonatol
January 2025
Department of Obstetrics and Gynecology, Sichuan University West China Second University Hospital, Chengdu, China.
Intrahepatic cholestasis of pregnancy (ICP) is a pregnancy-specific liver disease characterized by pruritus and elevated total bile acid (TBA) levels. The most serious impact of ICP is sudden unexplained intrauterine fetal death, especially when an associated TBA ≥ 100 µmol/L is confirmed.We report a case of a 27-year-old female patient with early-onset severe refractory ICP.
View Article and Find Full Text PDFDeveloping predictive models for assessing LC of organic contaminants in Gammarus species using interpretable structural parameters.
Aquat Toxicol
January 2025
Department of Chemistry, Semnan University, Iran.
Gammarus species are crucial indicators of environmental health, making them important for ecological studies and water quality assessments. They offer a wide range of specific responses regarding the median lethal concentration (LC) of organic compounds. This research presents four predictive models to determine the LC of chemicals impacting selected gammarid amphipods: Gammarus lacustris, Gammarus fasciatus, Gammarus pulex, and Gammarus pseudolimnaeus.
View Article and Find Full Text PDFMitochondrial dysfunction is a major cause of thromboinflammation and inflammatory cell death in critical illnesses.
Inflamm Res
January 2025
Department of Anesthesiology, Critical Care, and Surgery, Duke University School of Medicine, Durham, NC, USA.
Background: Mitochondria generate the adenosine triphosphate (ATP) necessary for eukaryotic cells, serving as their primary energy suppliers, and contribute to host defense by producing reactive oxygen species. In many critical illnesses, including sepsis, major trauma, and heatstroke, the vicious cycle between activated coagulation and inflammation results in tissue hypoxia-induced mitochondrial dysfunction, and impaired mitochondrial function contributes to thromboinflammation and cell death.
Methods: A computer-based online search was performed using the PubMed and Web of Science databases for published articles concerning sepsis, trauma, critical illnesses, cell death, mitochondria, inflammation, coagulopathy, and organ dysfunction.
Dye sensitized solar cells: Meta-analysis of effect sensitizer-type on photovoltaic efficiency.
Heliyon
January 2025
Grupo de Investigación en Fotoquímica y Fotobiología, Programa de Química, Facultad de Ciencias Básicas, Universidad Del Atlántico, Puerto Colombia, 81007, Colombia.
Since Dye-Sensitized Solar Cells (DSSCs) was created, a versatile and cost-effective alternative among photovoltaic technology options for power generation and energy transition to combat climate change have emerged. The theoretical and experimental knowledge of DSSCs have increased in regard to their operation in the last three decades of development; it includes the device's components, as well as the most recent innovations in their application and forms of activation. In this work paper, we presented a meta-study of photovoltaic characterization parameters, 329 scientific reports of DSSCs were considered to compare three types of sensitizers (Organometallics, non-metal organic dyes and, natural dyes).
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