Purpose: To reduce the rate of median nerve injury occurring during Chow's original 2-portal technique, we developed a modified procedure. The surgical technique was introduced, and the results were evaluated with regard to the clinical findings, nerve conduction studies, and Disabilities of the Arm, Shoulder, and Hand (DASH) score.
Methods: We analyzed 119 hands of 119 patients with idiopathic carpal tunnel syndrome who underwent our procedure, wherein a cannula assembly was inserted after a partial division of both distal and proximal parts of the transverse carpal ligament through the entry and exit portals. Postoperative examinations, including evaluation of numbness, grip strength, pinch strength, tenderness over and around the wounds, and nerve conduction studies, were performed at 1 month (n = 119), 3 months (n = 119), 6 months (n = 102), and 12 months (n = 39). The DASH score was also evaluated preoperatively and at 3, 6, or 12 months postoperatively. The rate of structural damage to the median nerve, the tendon, and the artery was calculated.
Results: The patients resumed their daily activities or work by 13 days postoperatively. Tenderness around the wounds was detected in 66% of patients by 3 months postoperatively. Numbness disappeared or decreased in 99% of patients by 6 months postoperatively. The DASH score was available for 82 patients, and it improved from 28.2 to 18.3 points postoperatively. Nerve conduction studies indicated a significant decrease in motor distal latency postoperatively. Temporal worsening of median nerve function was observed in 2 patients; however, no structural damage to the nerve, tendon, or artery was observed.
Conclusions: We found no injury to the tendon or artery and no laceration to the nerve in all 119 patients. However, temporal worsening of median nerve function was observed in 2 patients.
Level Of Evidence: Level IV, therapeutic case series.
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http://dx.doi.org/10.1016/j.arthro.2007.02.009 | DOI Listing |
J Clin Med
January 2025
Operative Research Unit of Anesthesia and Intensive Care, Fondazione Policlinico Universitario Campus Bio-Medico, Via Alvaro del Portillo, 200-00128 Roma, Italy.
Thoracic outlet syndrome (TOS) is an uncommon condition defined by the compression of neurovascular structures within the thoracic outlet. When conservative management strategies fail to alleviate symptoms, surgical decompression becomes necessary. The purpose of this study is to evaluate and compare the efficacy and safety of regional anesthesia (RA) using spontaneous breathing in contrast to general anesthesia (GA) for patients undergoing surgical intervention for TOS.
View Article and Find Full Text PDFLife (Basel)
January 2025
Department of Occupational Medicine, University of Medicine and Pharmacy of Craiova, 2 Petru Rares Str., 200349 Craiova, Romania.
: Carpal tunnel syndrome (CTS) is a common peripheral neuropathy, often assessed using the Boston Carpal Tunnel Questionnaire (BCTQ). The BCTQ evaluates symptom severity (SSS) and functional status (FSS) but has limitations in stratifying CTS severity, particularly in severe cases. : This study aimed to evaluate the utility of the BCTQ in a homogeneous cohort of female workers engaged in repetitive manual tasks, exploring its correlation with objective clinical measures and its performance in detecting CTS severity.
View Article and Find Full Text PDFGenes (Basel)
January 2025
Division of Cell and Developmental Genetics, Department of Medicine, Veterans Affairs Medical Center, and the Institute for Human Genetics, University of California, San Francisco, CA 94121, USA.
TSPX is an X-linked tumor suppressor that was initially identified in non-small cell lung cancer (NSCLC) cell lines. However, its expression patterns and downstream mechanisms in NSCLC remain unclear. This study aims to investigate the functions of TSPX in NSCLC by identifying its potential downstream targets and their correlation with clinical outcomes.
View Article and Find Full Text PDFBMC Ophthalmol
January 2025
Division of Ophthalmology, Ann & Robert H. Lurie Children's Hospital of Chicago, 225 E. Chicago Ave, Chicago, IL, 60611, United States of America.
Background: Congenital cytomegalovirus (CMV) infections are associated with eye manifestations, especially in patients with systemic disease. However, there are no ophthalmic screening guidelines for infants with congenital CMV.
Methods: Retrospective review of pediatric patients (< 18 years old, 2010-2023) with a diagnosis of congenital CMV and at least 1 eye examination.
J Neurodev Disord
January 2025
Department of Radiology, The First Affiliated Hospital of Sun Yat-sen University, No 58 Zhongshan 2nd Road, Guangzhou, 510080, China.
Background: Spinal muscular atrophy (SMA) is caused by reduced expression of survival motor neuron (SMN) protein. Previous studies indicated SMA causes not only lower motor neuron degeneration but also extensive brain involvement. This study aimed to investigate the changes of brain white matter and structural network using diffusion tensor imaging (DTI) in children with type 2 and 3 SMA.
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