Tracheal replacement is an uncommon option because of the very limited number of indications and the large number of possibilities for resection anastomosis. There may nevertheless be situations were extensive resection leaves only one solution, tracheal replacement. To date, no prosthesis has provided long-term satisfaction. For tracheal replacement, the prosthesis must provide a large caliber airway which does not collapse during expiration and which enables the development of a ciliary lining, in addition to tolerance without rejection. Recent experimental work, then several clinical cases, would suggest that the abdominal aorta can be successfully transformed into a neotrachea. A temporary endoprosthesis is however necessary to prevent collapse until new tracheal rings develop. Experimental and early clinical work has provided promising results but with problems concerning the endoprosthesis. In our patient, we used the abdominal aorta as a tracheal substitute but replaced the endoprosthesis with an exoprosthesis leaving the aortic lumen free. The result was also encouraging, but the absence of integration of the aortic tissue did not confirm the observations reported by others. Other hypotheses concerning the regeneration of the neotrachea should be put forward.
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http://dx.doi.org/10.1016/s0761-8417(07)90127-3 | DOI Listing |
CNS Neurosci Ther
January 2025
Beijing Key Laboratory of Hypoxia Translational Medicine, Xuanwu Hospital, Center of Stroke, Beijing Institute of Brain Disorder, Capital Medical University, Beijing, China.
Objective: Ischemia-reperfusion of the abdominal aorta often results in damage to distant organs, such as the heart and brain. This cellular heterogeneity within affected tissues complicates the roles of specific cell subsets in abdominal aorta occlusion model (AAO) injury. However, cell type-specific molecular pathology in the hippocampus after ischemia is poorly understood.
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January 2025
Department of Vascular Surgery, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China.
Abdominal aortic aneurysm represents a critical pathology of the aorta that currently lacks effective pharmacological interventions. TNF receptor-associated factor 6 (TRAF6) has been established to be involved in cardiovascular diseases such as atherosclerosis, hypertension, and heart failure. However, its role in abdominal aortic aneurysm (AAA) remains unclear.
View Article and Find Full Text PDFCureus
December 2024
Vascular Surgery, King Saud Medical City, Riyadh, SAU.
Aortoenteric fistula (AEF) is an abnormal connection between the aorta and the adjacent gastrointestinal (GI) tract and is often misdiagnosed in clinical practice. We present the case of a 65-year-old male, who presented with upper GI bleeding and melena. The patient underwent upper and lower GI examinations with no conclusive findings.
View Article and Find Full Text PDFAnn Pediatr Cardiol
December 2024
Department of Cardiovascular Radiology and Endovascular Interventions, All India Institute of Medical Sciences, Delhi, India.
Kawasaki disease, traditionally classified as medium vessel vasculitis, is known for the preferential involvement of coronary arteries. Infrequently, large systemic arteries might be involved and may affect the prognosis. Here, we present an infant with Kawasaki disease who had extensive involvement of large vessels such as the abdominal aorta and medium vessels of the extremities, along with giant coronary artery aneurysms.
View Article and Find Full Text PDFBMJ Case Rep
January 2025
General Surgery, Betsi Cadwaladr University Health Board, Bangor, UK
A woman in her 70s with hypertension, breast cancer and diverticulosis underwent laparoscopic anterior resection for a tubule-villous adenoma, converted to open Hartmann's with aorto-bi-iliac bypass due to a vascular injury. Intraoperative complications included haem-o-lok penetration of the calcified aorta, necessitating vascular team intervention. Postoperative issues included bilateral popliteal artery emboli requiring embolectomy and fasciotomy, and a parastomal abscess.
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