AI Article Synopsis
- A 14-year-old female black spider monkey (Ateles paniscus) was found to have a neuroendocrine tumor in her lung during a necropsy after sudden death.
- The tumor appeared as multiple firm nodular masses and was characterized histologically by polygonal cells in small aggregates, with specific nuclear features and a fibrovascular stroma.
- Immunohistochemical tests indicated that the tumor was positive for cytokeratin, chromogranin A, and synaptophysin, marking it as an atypical neuroendocrine tumor, and this is the first documented case of such a tumor in this monkey species.
Article Abstract
This paper describes a neuroendocrine (NE) tumor of the lung that was observed during the necropsy of a 14-year-old female black spider monkey (Ateles paniscus) with sudden death. Grossly, multifocal firm and coalescing nodular masses were observed in the lung. The histological examination showed the tumor to be an typical NE tumor with polygonal cells grouped in small solid aggregates, with regularly sized, spherical, centrally placed nuclei with modest, lightly granular cytoplasm suspended in a fibrovascular stroma. The immunohistochemical examination revealed the tumor to be positive for cytokeratin, chromogranin A and synaptophysin, and negative for CD56. To the best of our knowledge, this is the first report of NE tumor in the lung of the black spider monkey.
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| http://dx.doi.org/10.1292/jvms.69.783 | DOI Listing |
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