Overall 392 patients with lymphosarcoma were under observation from 1980 to 1989 at the department of childhood hematology, All-Union Cancer Research Center, USSR AMS. The patients were characterized by the moment of the disease diagnosis. During treatment, 70 patients (31%) developed disease relapses. The relapses were characterized, possible causes of their development were analyzed. The results of relapses treatment according to two programs are discussed. No increase of the survival of the patients with relapses due to the intensification of the treatment programs was noted.
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