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Pharmacotherapy for behavioural manifestations in frontotemporal dementia: An expert consensus from the European Reference Network for Rare Neurological Diseases (ERN-RND).
Eur J Neurol
December 2024
Department of Neurology, University Hospital Leuven, Leuven, Belgium.
Background And Purpose: Frontotemporal dementia (FTD) is a neurodegenerative disorder characterized by pervasive personality and behavioural disturbances with severe impact on patients and caregivers. In current clinical practice, treatment is based on nonpharmacological and pharmacological approaches. Unfortunately, trial-based evidence supporting symptomatic pharmacological treatment for the behavioural disturbances in FTD is scarce despite the significant burden this poses on the patients and caregivers.
View Article and Find Full Text PDF[Wakefulness-promoting agents for severe fatigue: to use or not to use?].
Ned Tijdschr Geneeskd
April 2024
St. Antonius Ziekenhuis, Nieuwegein en Utrecht. Afd. Neurologie en Klinische Neurofysiologie.
About 20% of adults experience excessive daytime sleepiness or severe fatigue. Causes include somatic conditions, psychiatric disorders, and medication or drug use. Treatment depends on the underlying cause.
View Article and Find Full Text PDFThe Association between Glucose 6-Phosphate Dehydrogenase Deficiency and Attention Deficit/Hyperactivity Disorder.
Nutrients
November 2023
Leumit Health Services, Tel Aviv 64738, Israel.
Article Synopsis
- * An analysis of 7,473 G6PD-deficient patients compared to 29,892 matched individuals showed these patients have a higher likelihood of being diagnosed with ADHD and seeking help from neurologists and psychiatrists.
- * The study found significantly increased usage of stimulant medications, with G6PD-deficient individuals having a 17% higher chance of using methylphenidate and a 16% increased risk for amphetamines.
Anxiety and Somatic Symptoms in Children and Adolescents Diagnosed with Attention-Deficit Hyperactivity Disorder.
Psychiatry J
August 2023
Faculty of Medicine, Department of Public Health, Sakarya University, Sakarya, Turkey.
Background: Attention-deficit hyperactivity disorder (ADHD) is a neurodevelopmental condition typified by inattention, hyperactivity, and impulsivity. Comorbid psychiatric disorders are common among children and adolescents with ADHD. In this study, it was aimed to examine anxiety and somatic symptoms in children and adolescents with ADHD and the effect of methylphenidate treatment on these symptoms.
View Article and Find Full Text PDFA Systematic Review of Treatments of Post-Concussion Symptoms.
J Clin Med
October 2022
Rehabilitation Unit, Rennes University Hospital, 2 Rue Henri Le Guilloux, 35000 Rennes, France.
Approximately 10−20% of patients who have sustained a mild Traumatic Brain Injury (mTBI) show persistent post-concussion symptoms (PCS). This review aims to summarize the level of evidence concerning interventions for PCS. Following the PRISMA guidelines, we conducted a systematic review regarding interventions for PCS post-mTBI until August 2021 using the Medline, Cochrane, and Embase databases.
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