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Primary intraosseous Rosai-Dorfman disease: Clinicopathological features and an assessment of a possible relationship with IgG4-related disease.
Ann Diagn Pathol
January 2025
Department of Pathology, Peking University People's Hospital, 100044, China.
Rosai-Dorfman disease (RDD) is a rare proliferative disorder of histiocytes, and primary solitary RDD of the bone is extremely rare. Some RDDs exhibit increased immunoglobulin (Ig)G4 positive (IgG4+) plasma cell infiltration and the histopathological features of IgG4-related disease (IgG4-RD). However, the association between RDD and IgG4-RD remains unclear.
View Article and Find Full Text PDFA rare case of solitary intraosseous neurofibroma of the mandible with radiological insights.
Radiol Case Rep
February 2025
Department of Psychiatry, Datta Meghe Institute of Medical Sciences, Sawangi, Wardha, Maharashtra, India 442001.
Neurofibromas (NF), rare benign peripheral nerve sheath tumors, are typically linked to neurofibromatosis type 1 (NF1). This case report presents a rare instance of a neurofibroma located in the mandible of a 12-year-old male patient, who presented with localized swelling and discomfort in the lower jaw. Clinical examination revealed a firm, nontender mass on palpation.
View Article and Find Full Text PDFPrimary Intraosseous Solitary Fibrous Tumor of the Mandible: Report of a Diagnostically Challenging Case with NAB2::STAT6 Fusion and Review of the Literature.
Head Neck Pathol
December 2024
Division of Oral and Maxillofacial Pathology, The Ohio State University, College of Dentistry, 305 W. 12th Ave, Columbus, OH, 43210, USA.
Introduction: Solitary fibrous tumor (SFT) represents an uncommon mesenchymal neoplasm affecting primarily the extremities and deep soft tissues with, overall, benign but locally aggressive biologic behavior and an underlying pathognomonic NAB2::STAT6 fusion. Intraosseous SFTs are infrequent, and involvement of the jawbones is exceedingly rare.
Case Presentation: A 54-year-old woman presented with an asymptomatic, well-demarcated, multilocular radiolucency of the left posterior mandible featuring focally irregular borders, root resorption and lingual cortex perforation.
Foreign body giant cell reaction due to Durolane (hyaluronic acid derivative) injection - A case report.
Skeletal Radiol
November 2024
Department of Radiology at UTHealth McGovern School of Medicine, The University of Texas Health Science Center at Houston, Houston, TX, USA.
Osteoarthritis can be treated with hyaluronic acid derivatives, such as Durolane manufactured by Bioventus (Hill, 2017), particularly when conventional treatments prove ineffective. In osteoarthritic joints, the synovial fluid has a lower concentration of hyaluronic acid compared to healthy joints. Intra-articular therapy with exogenous hyaluronic acid can improve viscoelastic properties, enhance chondrocyte synthesis, reduce cartilage degradation, and alleviate pain associated with osteoarthritis (Migliore and Procopio in Clin Cases Miner Bone Metab.
View Article and Find Full Text PDFSolitary Intraosseous Myofibroma of the Mandible in a Nine-Year-Old Child: A Case Report and Literature Review.
Cureus
July 2024
Pathology, Temple University Hospital, Philadelphia, USA.
Myofibroma (MF) is a benign neoplasm derived from myofibroblasts. While they are infrequent, these tumors are predominantly found in the pediatric group and seldom manifest as intraosseous mandibular tumors. Herein, we present a 9-year-old female with a radiolucent lesion in the left mandible associated with malposed left lower canine and 1st premolar teeth.
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