The range of factor Vlll (FVlll) is known to be very wide and its elevated concentration is a risk factor of thromboses. This paper describes a simple and available laboratory method for determining the high level of coagulation FVlll. Moreover, the results of determination of FVlll levels in 102 patients were used to study the incidence of thrombophilia due to FVlll hyperproduction in a region of Western Siberia.

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