Severity: Warning
Message: file_get_contents(https://...@pubfacts.com&api_key=b8daa3ad693db53b1410957c26c9a51b4908&a=1): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests
Filename: helpers/my_audit_helper.php
Line Number: 176
Backtrace:
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 176
Function: file_get_contents
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 250
Function: simplexml_load_file_from_url
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 1034
Function: getPubMedXML
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 3152
Function: GetPubMedArticleOutput_2016
File: /var/www/html/application/controllers/Detail.php
Line: 575
Function: pubMedSearch_Global
File: /var/www/html/application/controllers/Detail.php
Line: 489
Function: pubMedGetRelatedKeyword
File: /var/www/html/index.php
Line: 316
Function: require_once
The aim of the review is to attract attention to the importance of a dynamic approach to symptoms of health and pathology. In this regard, long-known approximately 24-hour or circadian rhythms (CR) are very prospective. However, according to recent studies, shorter approximately hourly rhythms (AHR) are of not less importance. Unlike CR, HR are not obtruded on the organism by periodical external influence of day-night pattern, but present cell's own fundamental property, a method of their metabolism. The fractal nature of HR has been substantiated; age-dependent changes in HR have been demonstrated; the importance of AHR for diagnostics and prognosis in gastroenterology and cardiology has been determined. To perform more clinical observations is an important task.
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