AI Article Synopsis
- HBL and HCC are the most prevalent liver cancers in children, and the effectiveness of liver transplants (OLT) for HCC is debated.
- A study analyzed records of 25 pediatric patients undergoing OLT, revealing that survival rates for those with HCC were high at one and five years (100% and 83.3%) compared to HBL and other reasons for transplant.
- The findings suggest that OLT is an effective treatment option for pediatric patients with liver malignancies.
Article Abstract
HBL and HCC are the most common hepatic malignancies in children. The role of OLT in children with HCC is still a matter of debate. The aim of this study was to review our experience of OLT for HCC. Medical records of patients (<18 yr) who underwent OLT for HCC were reviewed and compared to children who underwent OLT for HBL and for indications other than malignancy. There were 25 patients: HCC (10 cases) and HBL (15 cases). The actuarial patient survival for HCC at one and five yr was 100% and 83.3%, for the HBL group the survival was 86.7% at both one and five yr, and for indications (n=377) other than malignancy the patient survival for pediatric OLT at our center was 87.7% and 84.7% at one and five yr, respectively. The actuarial recurrence free survival at five yr was 83.3% for HCC and 66.8% for HBL. In conclusion, OLT is a good therapeutic modality for children with HCC and HBL.
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| http://dx.doi.org/10.1111/j.1399-3046.2007.00751.x | DOI Listing |
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