Death of a living liver donor from illicit drugs.

Liver Transpl

Department of Surgery, Center for Liver, Biliary and Pancreas Disease, Drexel University College of Medicine, Philadelphia, PA 19102, USA.

Published: August 2007

AI Article Synopsis

  • Living donor transplantation is proposed for parents of children with acute hepatic failure when deceased donor organs are unavailable.
  • The case involved a 36-year-old woman who died from a drug overdose after donating part of her liver to her son, who was suffering from liver failure due to acetaminophen intoxication.
  • The ethical dilemma arises from questioning whether her death was preventable, as her drug use was a personal choice, yet the urgency of the son's condition left little time for alternative solutions.

Article Abstract

In children with acute hepatic failure, it has been suggested to offer living donor transplantation to all parents when a deceased donor organ can not be provided. Ethically, living related donation is coercive by its very nature, especially in emergencies. We report a 36-year-old woman who died from a drug overdose 57 days after living donor liver resection. The recipient was her 3-year-old son, who experienced acute hepatic failure as a result of acetaminophen intoxication. A deceased donor organ had not become available within 2 days after listing. Was the death of this living donor preventable or unpreventable? Certainly if the mother had decided not to take drugs, she would not have died from an overdose. One could argue that this was her personal choice, and beyond our influence. On the other hand, if we had not performed the surgery, the recipient might have died without receiving a liver transplant in time.

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Source
http://dx.doi.org/10.1002/lt.21240DOI Listing

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