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Global leukemia burden and trends: a comprehensive analysis of temporal and spatial variations from 1990-2021 using GBD (Global Burden of Disease) data.
BMC Public Health
January 2025
Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian, People's Republic of China.
Background: Leukemia, a group of malignant tumors, has been a significant public health concern due to its high incidence and mortality rates. This study aimed to provide an in-depth analysis of the global leukemia burden from 1990 to 2021 using the Global Burden of Disease (GBD) database, focusing on trends in incidence, mortality, and Disability-Adjusted Life Years (DALYs) across different regions, genders, and age groups including forecasting future trends.
Methods: Data were sourced from the GBD study, utilizing the Global Health Data Exchange (GHDx) query tool.
Prehospital lactate analysis in suspected sepsis improves detection of patients with increased mortality risk: an observational study.
Crit Care
January 2025
Department of Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden.
Background: Rapid, adequate treatment is crucial to reduce mortality in sepsis. Risk stratification scores used at emergency departments (ED) are limited in detecting all septic patients with increased mortality risk. We assessed whether the addition of prehospital lactate analysis to clinical risk stratification tools improves detection of patients with increased risk for rapid deterioration and death in sepsis.
View Article and Find Full Text PDFFrequency of consumption and factors associated with hookah use in Curitiba, Brazil: a cross-sectional study.
BMC Public Health
January 2025
Escola de Medicina e Ciências da Vida, Pontifícia Universidade Católica do Paraná, Imaculada Conceição, 1155, Prado Velho, Curitiba, PR, CEP 8021, Brazil.
Objective: To analyze the consumption frequency and factors associated with hookah usage.
Methods: This cross-sectional study involved adults, hookah users, residing in the city of Curitiba. Hookah groups were contacted on social networking sites via an invitation that contained a link to the questionnaire, which comprised 21 questions covering demographic and socioeconomic characteristics, user profiles, use of cigarettes and alcohol, symptoms, and perceptions of the risks of hookah use.
Prenatal maternal stress: triangulating evidence for intrauterine exposure effects on birth and early childhood outcomes across multiple approaches.
BMC Med
January 2025
PsychGen Center for Genetic Epidemiology and Mental Health, Norwegian Institute of Public Health, Oslo, Norway.
Background: Maternal stress during pregnancy may impact offspring development via changes in the intrauterine environment. However, genetic and environmental factors shared between mothers and children might skew our understanding of this pathway. This study assesses whether prenatal maternal stress has causal links to offspring outcomes: birthweight, gestational age, or emotional and behavioral difficulties, triangulating across methods that account for various measured and unmeasured confounders.
View Article and Find Full Text PDFA realist evaluation to explain and understand the role of paramedics in primary care.
BMC Med
January 2025
Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.
Background: In response to the unsustainable workload and workforce crises in primary care, paramedics (with their generalist clinical background acquired from ambulance service experience) are increasingly employed in primary care. However, the specific contribution paramedics can offer to the primary care workforce has not been distinctly outlined. We used realist approaches to understand the ways in which paramedics impact (or not) the primary care workforce.
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