AI Article Synopsis
- The gastrointestinal tract is essential for converting and absorbing food, with both our body processes and resident microorganisms, especially in the small intestine, playing key roles in nutrient supply.
- To study the small intestine's microbial diversity and functionality, researchers have created various model systems since direct sampling can be challenging.
- Recent advancements in metagenomics are enhancing our understanding of these microbial communities' genetic potential and functional roles in the human gastrointestinal tract, particularly in the small intestine.
Article Abstract
The gastrointestinal tract is the main site where the conversion and absorption of food components takes place. The host-derived physiological processes and the residing microorganisms, especially in the small intestine, contribute to this nutrient supply. To circumvent sampling problems of the small intestine, several model systems have been developed to study microbial diversity and functionality in the small intestine. In addition, metagenomics offers novel possibilities to gain insight into the genetic potential and functional properties of these microbial communities. Here, an overview is presented of the most recent insights into the diversity and functionality of the microorganisms in the human gastrointestinal tract, with a focus on the small intestine.
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| http://dx.doi.org/10.2217/17460913.2.3.285 | DOI Listing |
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