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Endoscopic Orbital Clearance/Debridement: A Potential Substitute for Orbital Exenteration in Rhino-orbital Mucormycosis.
Int Arch Otorhinolaryngol
January 2025
Department of Otorhinolaryngology, Faculty of Medicine, Zagazig University, Egypt.
Mucormycosis is an aggressive, lethal fungal infection affecting the nasal and paranasal territory in immunocompromised patients. Orbital involvement is not uncommon and may require orbital exenteration. The management of orbital involvement in invasive fungal sinusitis is challenging, ranging from conservative retrobulbar amphotericin B injection in the early stages to orbital exenteration in late stages.
View Article and Find Full Text PDFA clinical study of rhino-orbital-cerebral mucormycosis during the COVID-19 pandemic in western Maharashtra.
J Family Med Prim Care
September 2024
Department of Ophthalmology, Dr. D.Y. Patil Medical College and Hospital, Pimpri, Pune, Maharashtra, India.
Background: The aim of the study was to describe the epidemiology and study the risk factors, clinical presentation, management, and outcome of rhino-orbital-cerebral mucormycosis (ROCM) in terms of mortality, exenteration, eye salvage, and vision salvage.
Methods: This retrospective, observational study was carried out over a period of two months. A detailed history was noted, and an ophthalmological examination was done.
Rapid Vision Loss After Root Canal Treatment Due to Invasive Fungal Sinusitis.
Ear Nose Throat J
September 2024
Department of Otolaryngology-Head and Neck Surgery, David Geffen School of Medicine of the University of California Los Angeles, Los Angeles, CA, USA.
Article Synopsis
- A 69-year-old diabetic woman developed acute invasive fungal rhinosinusitis (AIFRS) after a root canal and experienced worsening symptoms like facial pain and vision loss.
- Initial evaluations missed the issue, but imaging later showed serious sinus complications, leading to surgery that confirmed the fungal infection, mucormycosis.
- Treatment involved antifungal medications and surgery, highlighting that early detection and quick action are crucial for positive outcomes, especially in patients with underlying health issues like diabetes.
Risk Factors of COVID-19 associated mucormycosis in Iranian patients: a multicenter study.
BMC Infect Dis
August 2024
Isfahan Eye Research Center, Department of Ophthalmology, Isfahan University of Medical Sciences, Isfahan, Iran.
Article Synopsis
- - The study assessed demographics, clinical details, and outcomes of 274 Iranian patients with COVID-19-associated mucormycosis (CAM), and found that most participants were middle-aged men with a mean age of 56.8 years.
- - Key risk factors for increased mortality included smoking, ICU admission, advanced CAM stages, and specific treatments, while systemic corticosteroid use was linked to lower mortality rates.
- - Results indicated that deceased patients had significantly worse visual acuity compared to those who survived, highlighting the importance of early detection and tailored interventions for CAM patients to enhance health outcomes.
Orbital preservation in the treatment of acute invasive fungal sinusitis.
Am J Otolaryngol
December 2024
Northwell, Department of Otolaryngology-Head & Neck Surgery, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, 2000 Marcus Ave., Suite 300, New Hyde Park, NY 11042-1069, United States of America. Electronic address:
Acute invasive fungal sinusitis (AIFS) is an aggressive disease with significant mortality and morbidity. Surgical debridement is a mainstay of treatment. However, orbital involvement may limit its efficacy and is an independent risk factor for mortality.
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