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Evaluating the association of depressive symptoms on serum folate and erythrocyte folate levels based on the 2017-2020 NHANES database.
Front Nutr
February 2025
Department of Acupuncture and Moxibustion, Shanghai University of Traditional Chinese Medicine, Shenzhen Hospital, Shenzhen, China.
Objective: To improve further the management of the nutritional status and dietary habits of depressed patients.
Methods: This study investigated the effect of different severity states of depressive symptoms on serum and erythrocyte folate levels using the Nutrition Examination Survey (NHANES) database from 2017 to 2020. We comprised a sample of 4,872 cases from NHANES database.
pH-Responsive DNA-Functionalized Liquid Metal-Organic Frameworks (L-MOFs) as Molecular Sponges for Ultrasensitive and Label-Free SERS Detection of Folic Acid.
Small
February 2025
Department of Laboratory Medicine at The Fourth Affiliated Hospital, Harbin Medical University, Harbin, 150086, China.
Although "hotspots" have been utilized to enhance Raman signals for detecting various biomolecules, precisely regulating "hotspot" dimensions within enhancement substrates remains a significant challenge. This study introduces a novel, easily fabricated surface-enhanced Raman spectroscopy sensor, T(OH⁻)/Ag@CC. This platform employs single-stranded DNA of adjustable lengths to mediate the self-assembly of silver nanoparticles (Ag NPs), resulting in a uniformly enhanced substrate with a spatially organized metal-organic frameworks architecture.
View Article and Find Full Text PDFLow folate biomarker concentrations are associated with increase the risk and severity of periodontitis in adults: A cross-sectional study based on the National Health and Nutrition Examination Survey 2009-2014.
Nutr Res
February 2025
College & Hospital of Stomatology, Anhui Medical University, Key Laboratory of Oral Diseases Research of Anhui Province, Hefei, China; Department of Epidemiology and Biostatistics, School of Public Health, Anhui Medical University, Hefei, China.
We sought to test the hypothesis that adult folate biomarker concentrations are negatively associated with the risk and severity of periodontitis. Data were pooled from the National Health and Nutrition Examination Survey (NHANES) 2009 to 2014. A total of 9252 dentate adult subjects aged 30 years and older who received a periodontal examination and had complete folate biomarker data were included in the analysis.
View Article and Find Full Text PDFCardiovascular disease attenuates the protective effect of folate on global cognitive function in an elderly population: a cross-sectional study.
Sci Rep
January 2025
Department of Cardiovascular, The First Affiliated Hospital, and College of Clinical Medicine of Henan University of Science and Technology, No. 24, Jinghua Road, Jianxi District, Luoyang, Henan Province, China.
Research suggests that folic acid contributes to improving cognitive function. However, there is a lack of systematic research on the association of dietary intake of folate and serum, and red blood cell (RBC) folate levels with global cognitive impairment (CoI) in the elderly population. Importantly, excessive supplementation with folate among American adults at high risk of cardiovascular disease (CVD) may have harmful effects.
View Article and Find Full Text PDFAssociation of folate levels with all-cause and cause-specific mortality in patients with arthritis.
Clin Rheumatol
March 2025
Department of Orthopedics, Wuxi No. 2 People's Hospital, Jiangnan University Medical Center, No. 68 Zhongshan Road, Wuxi, Jiangsu, 214001, China.
Objective: The purpose of this study was to examine the association of folate levels, including red blood cell (RBC) and serum folate with mortality (cardiovascular disease (CVD)-related, all-cause, and cancer-related) in patients with arthritis.
Methods: We integrated and analyzed the data from the 1999-2018 National Health and Nutrition Examination Survey to conduct this study. Weighted Cox proportional hazard regression, restricted cubic spline (RCS) model, and subgroup analysis were used to analyze the association of RBC and serum folate levels with all-cause, cancer-related, and CVD-related mortality.
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