Background: Retroperitoneal leiomyosarcomas are neoplasma which are best treated with complete exeresis.
Aim: We reported three new cases of retroperitoneal Leiomyosarcoma operated during last ten years.
Cases: The authors reported 3 cases of Retroperitoneal leiomyosarcomas in 3 patients (2 men and a woman) aged respectively 53, 55 and 57 year-old. Incomplete resection was performed in the 3 cases because of the important local extension. All patients died 18, 19 et 51 months after diagnosis.
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Int J Surg Case Rep
November 2024
Department of Surgery A La Rabta Hospital, Tunis, Tunisia; Faculty of medicine of Tunis, Tunis El Manar University, Tunis, Tunisia.
Introduction And Importance: While the treatment approach for sarcomas seems straightforward and well-defined, we often encounter several diagnostic or therapeutic challenges in clinical practice. This article presents a case of retroperitoneal leiomyosarcoma in a patient with chronic kidney disease, highlighting the complexity of managing such cases.
Case Report: A 63-year-old woman with a history of chronic kidney disease presented with a progressively enlarging mass in her right flank.
Ann Surg Oncol
December 2024
Department of Surgery, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
Background: In 2023 and 2024, a wide variety of new studies have been published in the field of soft tissue sarcomas, representing the enormous heterogeneity of sarcoma histotypes, anatomical location, treatment variability, and biological behavior.
Patients And Methods: This article summarizes the, in our view, seven most important publications in the field that will have an impact on the surgical practice and future treatment strategies of our patients.
Results: In the last year, we gained more insight in the genetic background of patients with sarcoma from a large Australian study, which will have an impact on future counseling and screening of our patients.
J Cancer Res Clin Oncol
November 2024
Department of Surgery, Sarcoma Unit, University Medical Center Mannheim (UMM) and Medical Faculty Mannheim, Heidelberg University, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany.
Purpose: Retroperitoneal sarcomas (RPS) are rare, heterogeneous tumours. Treatment recommendations are mainly derived from cohorts treated at reference centres. The applicability of data from cancer registries (CR) is controversial.
View Article and Find Full Text PDFGan To Kagaku Ryoho
October 2024
Dept. of Surgery, Kindai University Hospital.
A 59-year-old man presented with abdominal mass and weight loss. Computed tomography revealed a 20 cm mass in the vicinity of the left kidney. A tumor biopsy was performed and diagnosed with leiomyosarcoma.
View Article and Find Full Text PDFIndian J Surg Oncol
December 2024
Department of Radio-Diagnosis, IRCH, All India Institute of Medical Sciences, New Delhi, 110029 India.
Primary inferior vena cava(IVC) leiomyosarcoma (LMS) is an extremely rare retroperitoneal mesenchymal tumour with < 500 cases reported in literature so far. Patients always present with nonspecific complaints, hence delaying the actual diagnosis, and they are associated with poor oncological outcomes. Differentiating primary leiomyosarcoma from other pathologies affecting IVC-like bland thrombus, retroperitoneal liposarcomas and other tumours infiltrating IVC secondarily may be difficult at times.
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