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Reorganization of cortical individualized differential structural covariance network is associated with regional morphometric changes in chronic subcortical stroke.
Neuroimage Clin
January 2025
Department of Radiology, Tianjin Key Lab of Functional Imaging & Tianjin Institute of Radiology, Tianjin Medical University General Hospital, Tianjin 300052, China. Electronic address:
Patients with chronic subcortical stroke undergo regional and network morphometric reorganizations beyond the lesion site, but the interplay between network and regional reorganization remains poorly understood. We aimed to clarify the reorganization patterns of the individualized differential structural covariance networks (IDSCN) in chronic subcortical stroke and investigate their associations with regional gray matter volume (GMV) changes and functional recovery. Structural MRI from four datasets enrolled 112 patients with chronic subcortical stroke (81 male, age: 55.
View Article and Find Full Text PDFEffectiveness of unilateral lower-limb exoskeleton robot on balance and gait recovery and neuroplasticity in patients with subacute stroke: a randomized controlled trial.
J Neuroeng Rehabil
December 2024
The Fifth Affiliated Hospital of Zhengzhou University, Henan, 450052, P.R. China.
Background: Impaired balance and gait in stroke survivors are associated with decreased functional independence. This study aimed to evaluate the effectiveness of unilateral lower-limb exoskeleton robot-assisted overground gait training compared with conventional treatment and to explore the relationship between neuroplastic changes and motor function recovery in subacute stroke patients.
Methods: In this randomized, single-blind clinical trial, 40 patients with subacute stroke were recruited and randomly assigned to either a robot-assisted training (RT) group or a conventional training (CT) group.
Soft partial release of non-aggressive stent retriever technique for very distal arterial occlusion stroke.
Interv Neuroradiol
November 2024
Department of Neuroradiology, University Hospital of Giessen and Marburg, Campus Marburg, Marburg, Germany.
Article Synopsis
- The study evaluates the safety and efficacy of a new technique called soft partial release of non-aggressive stent retrievers (SPORNS) for treating very distal vessel occlusion strokes.
- There were 24 patients treated with this method, resulting in a high recanalization success rate (92%) and significant improvement in patient outcomes, as indicated by reduced NIHSS scores and a majority achieving good outcomes by day 90.
- The SPORNS technique seems to reduce the risk of bleeding complications while effectively treating small clots in distal arteries.
Polygenic Risk of Epilepsy and Poststroke Epilepsy.
Stroke
December 2024
Department of Neurology, University of Gothenburg, Göteborg, Sweden (S.C.-T., C.A.R., S.M., L.H.S., A.d.H., L.J.H., E.J.G., K.N.S., J.A.K., G.J.F., N.K.M.).
Background: Epilepsy is highly heritable, with numerous known genetic risk loci. However, the genetic predisposition's role in poststroke epilepsy (PSE) remains understudied. This study assesses whether a higher genetic predisposition to epilepsy raises poststroke survivor's risk of PSE.
View Article and Find Full Text PDFLink between post-stroke psychopathology and scope-of-action awareness.
Ther Adv Neurol Disord
October 2024
Faculty of Science, Medical School Berlin, Berlin, Germany.
Background: Epidemiological research has failed to confirm laterality of lesion site as a neurobiological source of post-stroke psychopathology. However, acquired communication disorders have proved to be a key risk factor for depression, apart from established parameters such as pre-stroke psychopathology and physical immobility.
Objectives: The present work examines a new predictor of post-stroke psychopathology: psychological flexibility.
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