Trijugin-type limonoids from the leaves of Cipadessa cinerascens.

J Nat Prod

State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, People's Republic of China.

Published: August 2007

AI Article Synopsis

  • Four new limonoids, named cipatrijugins A-D, along with the known compound cipadesin A, were extracted from Cipadessa cinerascens leaves.
  • Their structures were determined using advanced spectroscopic and computational techniques.
  • The growth-inhibiting effects of these compounds on A549 and K562 tumor cell lines were tested.

Article Abstract

Four new trijugin-type limonoids, cipatrijugins A-D (1-4), together with the known cipadesin A (5), were isolated from the leaves of Cipadessa cinerascens, and their structures were elucidated on the basis of spectroscopic and computational methods. The ability of compounds 1-5 to inhibit the growth of the A549 and K562 tumor cell lines was evaluated.

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Source
http://dx.doi.org/10.1021/np0700624DOI Listing

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