[Study on effect of different extracts in curcuma long on stability of curcumin].

Zhongguo Zhong Yao Za Zhi

Pharmaceutical Department, North China Coal Medical College, Tangshan Key Laboratory of New Drug Research, Tangshan 063000, China.

Published: May 2007

AI Article Synopsis

  • The study aimed to explore how different extracts from Curcuma long can stabilize curcumin and prevent its degradation.
  • Researchers used various solvents (like alcohol and acetone) to add to pure curcumin and analyzed its stability using high performance liquid chromatography (HPLC).
  • The findings showed that alcohol extracts, especially 80% alcohol, significantly improved the stability of curcumin compared to its pure form.

Article Abstract

Objective: To investigate effects of different extracted fractions from Curcumia long on the stability of curcumin. There are some constituents that can stabilize curcumin.

Method: To add the extracts obtained from C. long were water, alcohol, acetone, ether, ethyl acetate, petroleum ether to pure solution of curcumin. To determine the change of curcumin by high performance liquid chromatography (HPLC). To investigate the dynamics of curcumin degradation.

Result: The stability obtained from alcohol, acetone, ether, ethyl ether all improved the stabilization of curcumin. 80% Alcohol extract had the optimal stabilizineg ability for curcumin.

Conclusion: The extracts from alcohol are more stable than pure curcumin at same conditions. The stability of curcumin is improved by alcohol extracts.

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