Albers Schonberg disease commonly called as osteopetrosis is a disorder involving defective bone resorption. The severe autosomal recessive form of osteopetrosis is very rare and characterised by abnormalities in skeletal bones, delayed psychomotor development, optic and facial nerve dysfunction, hydrocephalus, anaemia, haematologic and bleeding disorder, and a diversity of other manifestation. We report a case of intracranial subdural haematoma following a trivial head injury in an infant with severe autosomal recessive form of osteopetrosis.
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http://dx.doi.org/10.1016/j.jcfm.2006.02.020 | DOI Listing |
JAMA Netw Open
January 2025
Department of Emergency Medicine, The Ohio State University, Columbus.
Importance: While national guidelines recommend avoidance of hypoxia, hypotension, and hypocarbia in the prehospital care of traumatic brain injury (TBI), limited data validate the association of these adverse physiologic events with TBI outcomes.
Objective: To validate the associations of prehospital hypoxia, hypotension, and hypocarbia with TBI outcomes in a US national trauma network.
Design, Setting, And Participants: This cohort study examined data from 8 level I trauma centers and their affiliated ground and air emergency medical services (EMS) agencies in the Linking Investigations in Trauma and Emergency Services (LITES) Network from January 1, 2017, to June 30, 2021.
Eur Radiol
January 2025
Trauma Research Unit, Department of Surgery, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.
Introduction: Injury coding with the Abbreviated Injury Scale (AIS) is an important element for benchmarking, trauma registries and research.
Objective: To compare the severity of traumatic brain injury (TBI) coding derived from the AIS with or without the use of a standardised radiologic template.
Methods: A retrospective two-centre cohort study including patients aged ≥ 18 years with isolated TBI admitted to an intensive care between 2011 and 2016 was conducted.
Am Surg
January 2025
Department of Surgery, Philadelphia College of Osteopathic Medicine, Philadelphia, PA, USA.
Background: The precautions brought on by the COVID-19 pandemic led to the growing practice of bundling lines in patients requiring intubation. Our study aims to examine the effect of immediate bundled lines (IBL) on traumatic injuries. We hypothesized that severely injured patients may benefit from IBL.
View Article and Find Full Text PDFS Afr J Surg
December 2024
Trauma and Burns Unit, Inkosi Albert Luthuli Central Hospital, South Africa.
Background: Data on trauma burden and outcome varies amongst the nine South African Provinces. In Limpopo Province there is a paucity of data which this study aimed to quantify and characterise the severe trauma burden in the province.
Methods: A retrospective chart review for all patients with injury severity score (ISS) > 16 over a 6-year period (Jan 2015-Dec 2020) at two central hospitals in Limpopo province.
Theranostics
January 2025
Department of Physiology & Medical Physics, RCSI University of Medicine & Health Sciences, Dublin D02 YN77, Ireland.
Post-traumatic epilepsy (PTE) is one of the most common life-quality reducing consequences of traumatic brain injury (TBI). However, to date there are no pharmacological approaches to predict or to prevent the development of PTE. The P2X7 receptor (P2X7R) is a cationic ATP-dependent membrane channel that is expressed throughout the brain.
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