Objective: To compare the results of detecting HIV-1 load by using NucliSens HIV-1 QT and Amplicor HIV-1 monitor 1.5 assays.

Methods: Eighty-two clinical samples were collected and HIV viral load was determined with the above-mentioned two methods.

Results: The number of samples in which values obtained by NucliSens HIV-1 QT and Amplicor HIV-1 monitor 1.5 differed by <0.5 log10 RNA copies/ml and in which the viral load was undetectable accounted for 88.9 percent of the measures. The correlation coefficient between the two methods was 0.956 in 56 samples of Deltalog10 VL<0.5.

Conclusion: The results of HIV-1 viral load determination with the two methods are highly comparable.

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