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Reducing Greenhouse Gas Emissions and Modifying Nitrous Oxide Delivery at Stanford: Observational, Pilot Intervention Study.
JMIR Perioper Med
January 2025
Stanford Hospital, Stanford, CA, United States.
Background: Inhalational anesthetic agents are a major source of potent greenhouse gases in the medical sector, and reducing their emissions is a readily addressable goal. Nitrous oxide (NO) has a long environmental half-life relative to carbon dioxide combined with a low clinical potency, leading to relatively large amounts of NO being stored in cryogenic tanks and H cylinders for use, increasing the chance of pollution through leaks. Building on previous findings, Stanford Health Care's (SHC's) NO emissions were analyzed at 2 campuses and targeted for waste reduction as a precursor to system-wide reductions.
View Article and Find Full Text PDFRegulation of automatic imitation: Domain-specific versus domain-general control processes.
J Exp Psychol Hum Percept Perform
January 2025
Department of Psychology, Rutgers University.
The tendency to automatically imitate others' behavior is well documented. Successful interactions with others require some control of automatic imitation, but the nature of these control mechanisms remains unclear. The present study investigated whether the regulation of automatic imitation involves domain-specific versus domain-general control processes.
View Article and Find Full Text PDFAre we systematically overdosing women? Revisiting standardized contrast protocols for thoracoabdominal CT scans.
Eur Radiol
January 2025
Department of Diagnostic and Interventional Radiology, University Hospital Augsburg, Augsburg, Germany.
Objectives: The purpose of this study was to evaluate whether the iodine contrast in blood and solid organs differs between men and women and to evaluate the effect of BMI, height, weight, and blood volume (BV) on sex-specific contrast in staging CT.
Materials And Methods: Patients receiving a venous-phase thoracoabdominal Photon-Counting Detector CT (PCD-CT) scan with 100- or 120-mL CM between 08/2021 and 01/2022 were retrospectively included in this single-center study. Image analysis was performed by measuring iodine contrast in the liver, portal vein, spleen, left atrium, left ventricle, pulmonary trunk, ascending and descending aorta on spectral PCD-CT datasets.
Biomarkers.
Alzheimers Dement
December 2024
Institute of Public and Preventative Health, Augusta, GA, USA.
Background: Physiological changes, including metabolic and cellular aging, as well as increased inflammation, occur in people living with dementia (PWD). While there is existing evidence in other populations suggesting that exercise may improve physiological outcomes, their impact in PWD remains unclear. This randomized controlled trial (RCT) aimed to assess the effects of exercise on serum levels of metabolic aging, cellular aging, and inflammatory blood biomarkers relative to usual care alone in PWD.
View Article and Find Full Text PDFBiomarkers.
Alzheimers Dement
December 2024
Dementia Research Centre, Queen Square Institute of Neurology, University College London, London, UK.
Background: GRN mutations are a common cause of frontotemporal dementia (FTD), with previous studies linking granulin deficiency to reduced bis(monoacylglycerol)phosphate (BMP) levels, which ultimately impairs ganglioside degradation. BMP is involved in the lysosomal functions within cells, as it facilitates the adhesion of hydrolases and activator proteins where the lysosomal membranes meet, therefore a lack of BMP could impact lysosome function and integrity. We hypothesised that urine levels of BMP isoforms will be lower in FTD patients with GRN haploinsufficiency, as a reflection of reduced BMP in neural tissues, when compared to those with FTD caused by C9orf72 expansions and MAPT mutations, or healthy controls.
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