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AI-Driven insights in pancreatic cancer imaging: from pre-diagnostic detection to prognostication.
Abdom Radiol (NY)
December 2024
Department of Radiology, Mayo Clinic, Rochester, MN, USA.
Pancreatic ductal adenocarcinoma (PDAC) is the third leading cause of cancer-related deaths in the United States, largely due to its poor five-year survival rate and frequent late-stage diagnosis. A significant barrier to early detection even in high-risk cohorts is that the pancreas often appears morphologically normal during the pre-diagnostic phase. Yet, the disease can progress rapidly from subclinical stages to widespread metastasis, undermining the effectiveness of screening.
View Article and Find Full Text PDFTurkish Society of Gastroenterology: Pancreas Working Group, Acute Pancreatitis Committee Consensus Report.
Turk J Gastroenterol
November 2024
Department of Gastroenterology, Mersin University School of Medicine, Mersin, Türkiye.
Acute pancreatitis (AP) is a clinical condition that arises acutely in the pancreas through various inflammatory pathways due to multiple causes. Turkish Society of Gastroenterology Pancreas Working Group developed comprehensive guidance statements regarding the management of AP that include its epidemiology, etiology, clinical presentation, diagnostic criteria, disease severity, treatment, prognosis, local and systemic complications. The statements were developed through literature review, deliberation, and consensus opinion.
View Article and Find Full Text PDFPancreatic Heterotopia in the Biliary Cyst Wall of a Pregnant Patient and Literature Review.
Int J Surg Pathol
November 2024
Department of General Surgery, Hacettepe University Faculty of Medicine, Ankara, Turkey.
Pancreatic heterotopia is the presence of pancreatic tissue in a different anatomical location with no connection to the main pancreas. The most common locations in the gastrointestinal system are duodenum, stomach, and Meckel diverticulum. However, it is quite rare in the hepatobiliary system.
View Article and Find Full Text PDFShedding light on pancreatic metastasis of clear cell sarcoma: An exceptional journey.
World J Clin Cases
September 2024
Veterinary Medicine, Chungbuk National University, Cheongju 28644, South Korea.
This editorial comments on the study by Liu investigating pancreatic metastasis of clear cell sarcoma (CCS) published in the . CCS is a rare and aggressive melanocytic tumor, that typically arises from tendons and aponeuroses of the limbs, and metastasizes to the lungs, bones, and brain. However, pancreatic metastasis has rarely been reported, presenting unique diagnostic and therapeutic challenges.
View Article and Find Full Text PDFExploring pancreatic beta-cell subgroups and their connectivity.
Nat Metab
November 2024
Department of Bioengineering, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Functional pancreatic islet beta cells are essential to ensure glucose homeostasis across species from zebrafish to humans. These cells show significant heterogeneity, and emerging studies have revealed that connectivity across a hierarchical network is required for normal insulin release. Here, we discuss current thinking and areas of debate around intra-islet connectivity, cellular hierarchies and potential "controlling" beta-cell populations.
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