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http://dx.doi.org/10.1128/EC.00173-07 | DOI Listing |
Trop Anim Health Prod
January 2025
Department of Micrology, College of Medicine, Taif University, Taif, 21944, Egypt.
Foot-and-mouth disease (FMD) continues to pose a significant threat in Egypt, necessitating thorough analyses of FMD virus (FMDV) outbreaks. This study analyzed 144 suspected FMD cases across 52 animal collections during the years 2017-2018 and 2022. Recurrent FMD outbreaks in vaccinated dairy cattle were investigated.
View Article and Find Full Text PDFThe human gut microbiome within the gastrointestinal tract continuously adapts to variations in diet, medications, and host physiology. A central strategy for genetic adaptation is epigenetic phase variation (ePV) mediated by bacterial DNA methylation, which can regulate gene expression, enhance clonal heterogeneity, and enable a single bacterial strain to exhibit variable phenotypic states. Genome-wide and site-specific ePV have been well characterized in human pathogens' antigenic variation and virulence factor production.
View Article and Find Full Text PDFUnlabelled: The spirochete causes Lyme disease. In some patients, an excessive, dysregulated proinflammatory immune response can develop in joints leading to persistent arthritis. In such patients, persistence of antigenic peptidoglycan (PG ) fragments within joint tissues may contribute to the immunopatho-genesis, even after appropriate antibiotic treatment.
View Article and Find Full Text PDFComp Immunol Microbiol Infect Dis
January 2025
Graduated Student in doctor of Veterinary Medicine, Faculty of Veterinary Medicine, Babol Branch, Islamic Azad University, Babol, Iran. Electronic address:
Canine distemper virus (CDV) causes a highly contagious and lethal disease in a vast range of carnivorous and non-carnivorous species. The study aimed to genetically investigate the hemagglutinin (H) gene and Fsp-coding region of CDV isolates from vaccinated dogs. Phylogenetic analysis of the H gene and Fsp-coding region showed that our viruses belonged to the Arctic-like lineage which was distinct from two commonly used vaccine strains (America-1 lineage strains) in Iran.
View Article and Find Full Text PDFMicrobiol Mol Biol Rev
January 2025
Department of Microbiology and Immunology, Weill Cornell Medical College, New York, New York, USA.
SUMMARYThe human malaria parasite is known for its ability to maintain lengthy infections that can extend for over a year. This property is derived from the parasite's capacity to continuously alter the antigens expressed on the surface of the infected red blood cell, thereby avoiding antibody recognition and immune destruction. The primary target of the immune system is an antigen called PfEMP1 that serves as a cell surface receptor and enables infected cells to adhere to the vascular endothelium and thus avoid filtration by the spleen.
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