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Development of Deep Learning-Based Virtual Lugol Chromoendoscopy for Superficial Esophageal Squamous Cell Carcinoma.
J Gastroenterol Hepatol
December 2024
Division of Gastroenterology and Hepatology, Department of Internal Medicine, School of Medicine, Iwate Medical University, Iwate, Japan.
Background: Lugol chromoendoscopy has been shown to increase the sensitivity of detection of esophageal squamous cell carcinoma (ESCC). We aimed to develop a deep learning-based virtual lugol chromoendoscopy (V-LCE) method.
Methods: We developed still V-LCE images for superficial ESCC using a cycle-consistent generative adversarial network (CycleGAN).
Comparative Efficacy and Safety of Endoscopic Modalities for Colorectal Cancer Screening in Inflammatory Bowel Disease: A Systematic Review and Network Meta-Analysis.
Clin Gastroenterol Hepatol
December 2024
Translational Gastroenterology Unit, Nuffield Department of Medicine, John Radcliffe Hospital, University of Oxford, Oxford, UK. Electronic address:
Background: Long-standing Inflammatory bowel disease (IBD) increases the risk of colonic neoplasia, necessitating effective screening strategies. This network meta-analysis (NMA) compared the efficacy and safety between different endoscopic modalities in the high-definition (HD) era.
Methods: We searched CENTRAL, ClinicalTrials.
Colonoscopy Remains an Important Option for Primary Screening for Colorectal Cancer.
Dig Dis Sci
December 2024
Division of Gastroenterology/Hepatology, Department of Medicine, Indiana University School of Medicine, Indianapolis, IN, USA.
Article Synopsis
- - Colonoscopy is the most commonly used screening test for colorectal cancer in the U.S., with high sensitivity for detecting precancerous lesions, allowing screenings every 10 years, and possibly every 15 years for those with normal results.
- - There is substantial evidence showing colonoscopy reduces colorectal cancer incidence and mortality, supported by various studies, including comparisons with other screening methods like flexible sigmoidoscopy.
- - Advances in colonoscopy techniques, such as improved mucosal exposure methods and non-device strategies, have enhanced detection rates of precancerous lesions, along with safer resection techniques for small lesions, increasing the effectiveness of this screening option.
Dye-based chromoendoscopy versus i-scan virtual chromoendoscopy in long-standing ulcerative colitis: Multicenter prospective RCT.
Endosc Int Open
November 2024
Department of Gastroenterology and Hepatology, University Hospital Leuven, Leuven, Belgium.
Long-standing ulcerative colitis (UC) is associated with an increased risk of developing colorectal neoplasia. Both dye-based chromoendoscopy (DCE) and virtual chromoendoscopy (VCE) increase detection of neoplastic lesions. In this prospective randomized controlled trial (RCT), we compared the neoplasia detection rate between DCE and i-scan VCE in patients with long-standing UC.
View Article and Find Full Text PDFIntroduction magnifying chromoendoscopy (MCE) and Endoscopic ultrasonograpty (EUS) are often used as diagnostic tools to estimate the depth of invasion in early colorectal cancers (CRCs). The aim of this study was to compare MCE with EUS in distinguishing between slight submucosal invasion (invasion depth <1000μm) and massively submucosal invasion in patients with early CRCs, since slight submucosal invasion is currently considered as an indication for endoscopic resection and submucosal cancer with massively submucosal invasion should be surgically treated due to an increased risk of lymph node metastasis. Methods For this meta-analysis, relevant studies were identified from PubMed, Embase and the Cochrane Library databases between the time of the establishment and April 2023.
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