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Phenotypic characterization and epidemiology of extended-spectrum -lactamase-producing strains from urinary tract infections in Garoua, Cameroon.
Front Public Health
July 2023
Department of Infectious Disease Epidemiology, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany.
Article Synopsis
- * Out of 144 bacterial isolates, 41% were found to be multidrug-resistant, with Escherichia coli being the most common (77.1%). The study also identified concerning rates of resistance to last-resort antibiotics but found Fosfomycin to be a consistently effective treatment option.
- * The findings underscore the need for improved treatment guidelines and antimicrobial stewardship to combat the growing threat of ESBL-E infections in the region.
Molecular characterization of extended-spectrum β-lactamases-producing Enterobacteriaceae species in ground beef and chicken meat.
Int J Food Microbiol
August 2023
Department of Biology, Faculty of Arts and Sciences, Amasya University, Amasya, Türkiye.
The objectives of this study were i) to characterize extended-spectrum β-lactamase-producing Enterobacteriaceae (ESBL-E) using pheno- and genotyping methods, ii) to evaluate the antimicrobial resistance pattern against 10 antibiotics, and iii) to investigate class 1 integron (intI1) in 80 Enterobacteriaceae isolates obtained from chicken meat (n = 40; 47 isolates) and ground beef (n = 40; 33 isolates) samples. Through the study, we found that 55 (68.7 %) of 80 Enterobacteriaceae isolates were capable of β-lactamase activity, and 38 (47.
View Article and Find Full Text PDFAntimicrobial resistance and metallo-beta-lactamase producing among commensal Escherichia coli isolates from healthy children of Khuzestan and Fars provinces; Iran.
BMC Microbiol
December 2020
Mathematical Sciences and Computer Faculty, Shahid Chamran University of Ahvaz, Ahvaz, Iran.
Background: The emergence of metallo-β-lactamase (MBL)-producing isolates is alarming since they carry mobile genetic elements with great ability to spread; therefore, early detection of these isolates, particularly their reservoir, is crucial to prevent their inter- and intra-care setting dissemination and establish suitable antimicrobial therapies. The current study was designed to evaluate the frequency of antimicrobial resistance (AMR), MBL producers and identification of MBL resistance genes in Escherichia coli strains isolated from fecal samples of the healthy children under 3 years old. A total of 412 fecal E.
View Article and Find Full Text PDFEvaluation of type II Toxin-Antitoxin Systems, Antibiotic Resistance Profiles, and Biofilm Quorum Sensing Genes in Acinetobacter Baumannii Isolates in Iraq.
Infect Disord Drug Targets
September 2021
Department of Biology, College of Science, Mustansiriyah University, Baghdad, Iraq.
Background: Bacterial Toxin-Antitoxin (TAs) systems are extensive two-component elements in the bacterial genome, which are involved in many key biological functions, including growth arrest, survival, biofilm formation, plasmid maintenance, defense against phages, persistence, and virulence.
Aim: This study aimed to assess the molecular determinants involved in TAs, biofilm quorum sensing, and antibiotic resistance profiles in Acinetobacter baumannii isolated from Baghdad's hospitals in Iraq.
Methods: A total of 127 A.
Molecular Epidemiology and Mechanisms of High-Level Resistance to Meropenem and Imipenem in .
Infect Drug Resist
January 2020
Microbiology and Immunology Department, Faculty of Pharmacy, Minia University, Minia, Egypt.
Purpose: possesses a large number of resistance mechanisms to different antimicrobials with carbapenems being the most powerful in treating resistant . Hence, it is imperative to explore different mechanisms of carbapenems-resistance in . aeruginosa to achieve successful treatment through the design of new drugs acting on this interaction to combat against antimicrobial resistance.
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